Proliposomal Ropivacaine Oil: Pharmacokinetic and Pharmacodynamic Data after Subcutaneous Administration in Volunteers

Keyphrases

• Pharmacokinetics 100%
• Pharmacodynamics 100%
• Subcutaneous Administration 100%
• Ropivacaine 100%
• Subcutaneous Injection 16%
• Heat Pain 16%
• Cmin 16%
• Confidence Interval 11%
• Area under the Curve 11%
• Local Anesthetics 11%
• Pinprick 11%
• Room Temperature 11%
• Liposomal 11%
• Slow Release 11%
• Peak Plasma Concentration 11%
• Pain Tolerance 11%
• High Dose 5%
• No Significant Difference 5%
• Pharmacodynamic Interactions 5%
• Anesthesia 5%
• Fold Increase 5%
• Clinical Applicability 5%
• Healthy Volunteers 5%
• Aqueous Media 5%
• Low Back 5%
• Plasma Concentration 5%
• Liposomal Formulation 5%
• Pharmacokinetic Study 5%
• Safe Administration 5%
• Depot 5%
• Quantitative Sensory Testing 5%
• Sensory Evaluation 5%
• Shelf Life 5%
• Lipid Vesicles 5%
• Pharmacokinetic Data 5%
• Terminal Half-life 5%
• Anesthesia Duration 5%
• Prediction Limits 5%
• Delayed Elimination 5%
• Multilamellar 5%
• Open-control 5%
• Plasma Drug Concentration 5%
• Shelf Stability 5%
• Sensory Effects 5%
• Simple Preparation 5%

Pharmacology, Toxicology and Pharmaceutical Science

• Pharmacodynamics 100%
• Subcutaneous Injection 100%
• Ropivacaine 100%
• Pharmacokinetics 100%
• Cmin 16%
• Local Anesthetic Agent 11%
• Normal Human 5%
• Elimination 5%
• Drug Concentration 5%