Profiling PIK3CA variants in disorders of somatic mosaicism

Keyphrases

• PIK3CA 100%
• Somatic Mosaicism 100%
• C2 Domain 30%
• Novel Variants 20%
• P110 20%
• Phosphoinositide 3-kinase (PI3K) 10%
• Cell Proliferation 10%
• Clinical Features 10%
• Next-generation Sequencing 10%
• Catalytic Subunit 10%
• Single Center 10%
• Clinical Presentation 10%
• Overgrowth 10%
• Genomic Services 10%
• Clinical Genomics 10%
• Vascular Malformation 10%
• Somatic mutations in Cancer 10%
• Cancer Database 10%
• Average Coverage 10%
• Laboratory-developed Test 10%

Biochemistry, Genetics and Molecular Biology

• Mosaicism 100%
• C2 Domain 30%
• Enzyme Active Site 10%
• Somatic Mutation 10%
• Next Generation Sequencing 10%
• Cell Proliferation 10%
• Clinical Genomics 10%