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Privileged scaffolds targeting reverse-turn and helix recognition
Ye Che
, Garland R. Marshall
Department of Biochemistry & Molecular Biophysics
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
Institute of Clinical and Translational Sciences (ICTS)
Research output
:
Contribution to journal
›
Review article
›
peer-review
35
Scopus citations
Overview
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Keyphrases
Protein-protein Interaction
100%
Helix
100%
Reverse Turns
100%
Privileged Scaffold
100%
Recognition Motif
75%
Protein Recognition
75%
Common Proteins
50%
Small Molecules
25%
Cellular Targets
25%
Protein Binding
25%
Recent Advances
25%
Molecular Recognition
25%
Small Molecule Inhibitors
25%
University of Washington
25%
Physiologic Conditions
25%
Proteinase Inhibitor
25%
Protein-peptide Complexes
25%
Relative Affinity
25%
Nonapeptides
25%
Drug Discovery
25%
Substructure
25%
Drug-like
25%
Bioavailable
25%
Binding Entropy
25%
Interaction-based
25%
Polyproline
25%
Ordered Structure
25%
Challenge-based
25%
Large Surfaces
25%
Privileged Structures
25%
Preorganization
25%
Chemical Template
25%
Reverse Helical
25%
Medicine and Dentistry
Protein-Protein Interaction
100%
Helix
100%
Receptor
20%
Biological Product
20%
Doctor of Philosophy
20%
DNA Template
20%
Biochemistry, Genetics and Molecular Biology
Protein-Protein Interaction
100%
Small Molecule
40%
Conformation
40%
Molecular Recognition
20%
DNA Template
20%
Drug Development
20%