Principles of radiation therapy for hodgkin lymphoma

Joachim Yahalom, Bradford S. Hoppe, Joanna C. Yang, Richard T. Hoppe

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations

Abstract

Radiation therapy (RT) remains a major component of the successful treatment of Hodgkin lymphoma (HL), even in the era of improved systemic therapies. For decades, definitive radiation was used alone to cure the majority of patients with HL, and it is still the most effective single agent in the oncologic armamentarium for this disease. RT as a single modality remains the treatment of choice for patients with early-stage lymphocyte-predominant HL (LPHL) and for a subset of patients with classic HL who have contraindications to chemotherapy. Currently, most patients with HL are treated with combined-modality programs in which RT is given as consolidation after chemotherapy. As the role of RT has transformed over the years from a single modality into an important component of combined-modality therapy, the classic principles of RT fields, dose, and technique have fundamentally changed.

Original languageEnglish
Title of host publicationHematologic Malignancies
PublisherSpringer
Pages171-197
Number of pages27
DOIs
StatePublished - 2020

Publication series

NameHematologic Malignancies
ISSN (Print)2197-9766
ISSN (Electronic)2197-9774

Keywords

  • Clinical target volume
  • Combined-modality
  • Deep-inspiration breath hold
  • Gross tumor volume
  • Hodgkin lymphoma
  • Involved-node radiation therapy
  • Involved-site radiation therapy
  • Planning target volume

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