Primary cutaneous rhabdomyosarcoma

Y. Chang, L. P. Dehner, B. Egbert

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26 Scopus citations

Abstract

We report an unusual case of primary cutaneous embryonal rhabdomyosarcoma presenting as a solitary skin lesion on the anterior chest of a 20-month-old child. The tumor was characterized by small, round to oval, poorly differentiated cells. Immunohistochemically, the tumor was negative for NSE, S-100 protein, LCA, and keratin but positive for muscle-specific actin, myoglobin, desmin, and vimentin, thus indicating the presence of myogenous differentiation. Ultrastructural analysis demonstrated thick and thin filaments. Special studies showed no evidence of a primary rhabdomyosarcoma in the patient at a more typical location, nor was there any evidence of metastases.

Original languageEnglish
Pages (from-to)977-982
Number of pages6
JournalAmerican Journal of Surgical Pathology
Volume14
Issue number10
DOIs
StatePublished - 1990

Keywords

  • Embryonal rhabdomyosarcoma
  • Rhabdomyosarcoma
  • Skin

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