Prevention of the Infected Fracture: Evidence-Based Strategies for Success!

Cyril Mauffrey, David J. Hak, David Rojas, Kent Doan, Brendan R. Southam, Michael T. Archdeacon, Martin Boyer, Michael McKee, Peter V. Giannoudis, Emil H. Schemitsch

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


There is a significant burden of disease associated with infected fractures, and their management is challenging. Prevention of infection after musculoskeletal trauma is essential because treatment of an established infection continues to be a major obstacle. Despite the need for evidence-based decision making, there is a lack of consensus around strategies for prevention and surgical management of the infected fracture. The current evidence for the prevention of the infected fracture is reviewed here with a focus on evidence for antibiotic therapy and debridement, the induced membrane technique, management of soft-tissue defects, patient optimization, and adjuncts to prevent infection.

Original languageEnglish
Pages (from-to)S1-S5
JournalJournal of orthopaedic trauma
StatePublished - Jun 1 2019


  • Antibiotics
  • Debridement
  • Induced membrane
  • Infected fracture
  • Musculoskeletal trauma
  • Patient optimization
  • Prevention
  • Soft-tissue defects


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