Prevention of the Infected Fracture: Evidence-Based Strategies for Success!

Cyril Mauffrey; David J. Hak; David Rojas; Kent Doan; Brendan R. Southam; Michael T. Archdeacon; Martin Boyer; Michael McKee; Peter V. Giannoudis; Emil H. Schemitsch

doi:10.1097/BOT.0000000000001469

Prevention of the Infected Fracture: Evidence-Based Strategies for Success!

Cyril Mauffrey, David J. Hak, David Rojas, Kent Doan, Brendan R. Southam, Michael T. Archdeacon, Martin Boyer, Michael McKee, Peter V. Giannoudis, Emil H. Schemitsch

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

There is a significant burden of disease associated with infected fractures, and their management is challenging. Prevention of infection after musculoskeletal trauma is essential because treatment of an established infection continues to be a major obstacle. Despite the need for evidence-based decision making, there is a lack of consensus around strategies for prevention and surgical management of the infected fracture. The current evidence for the prevention of the infected fracture is reviewed here with a focus on evidence for antibiotic therapy and debridement, the induced membrane technique, management of soft-tissue defects, patient optimization, and adjuncts to prevent infection.

Original language	English
Pages (from-to)	S1-S5
Journal	Journal of orthopaedic trauma
Volume	33
DOIs	https://doi.org/10.1097/BOT.0000000000001469
State	Published - Jun 1 2019

Keywords

Antibiotics
Debridement
Induced membrane
Infected fracture
Musculoskeletal trauma
Patient optimization
Prevention
Soft-tissue defects

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10.1097/BOT.0000000000001469

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title = "Prevention of the Infected Fracture: Evidence-Based Strategies for Success!",

abstract = "There is a significant burden of disease associated with infected fractures, and their management is challenging. Prevention of infection after musculoskeletal trauma is essential because treatment of an established infection continues to be a major obstacle. Despite the need for evidence-based decision making, there is a lack of consensus around strategies for prevention and surgical management of the infected fracture. The current evidence for the prevention of the infected fracture is reviewed here with a focus on evidence for antibiotic therapy and debridement, the induced membrane technique, management of soft-tissue defects, patient optimization, and adjuncts to prevent infection.",

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AU - Mauffrey, Cyril

AU - Hak, David J.

AU - Rojas, David

AU - Doan, Kent

AU - Southam, Brendan R.

AU - Archdeacon, Michael T.

AU - Boyer, Martin

AU - McKee, Michael

AU - Giannoudis, Peter V.

AU - Schemitsch, Emil H.

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KW - Antibiotics

KW - Debridement

KW - Induced membrane

KW - Infected fracture

KW - Musculoskeletal trauma

KW - Patient optimization

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Prevention of the Infected Fracture: Evidence-Based Strategies for Success!

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Keywords

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