Prevention of Surgical Site Infection

John P. Kirby, John E. Mazuski

Research output: Contribution to journalReview articlepeer-review

98 Scopus citations


Surgical site infections are a frequent cause of morbidity following surgical procedures. Gram-positive cocci, particularly staphylococci, cause many of these infections, although gram-negative organisms are also frequently involved. The risk of developing a surgical site infection is associated with a number of factors, including aspects of the operative procedure itself, such as wound classification, and patient-related variables, such as preexisting medical conditions. Both nonpharmacologic measures and antimicrobial prophylaxis for selected procedures are used to prevent development of these infections. Compliance with these generally accepted preventive principles may lead to overall decreases in the incidence of these infections.

Original languageEnglish
Pages (from-to)365-389
Number of pages25
JournalSurgical Clinics of North America
Issue number2
StatePublished - Apr 2009


  • Antibiotic prophylaxis
  • Antimicrobial agents
  • Infection control
  • Methicillin-resistant Staphylococcus aureus
  • Staphylococcus aureus
  • Surgical site infection
  • Surgical wound infection


Dive into the research topics of 'Prevention of Surgical Site Infection'. Together they form a unique fingerprint.

Cite this