Prevention of Recurrent Staphylococcal Skin Infections

C. Buddy Creech; Duha N. Al-Zubeidi; Stephanie A. Fritz

doi:10.1016/j.idc.2015.05.007

Prevention of Recurrent Staphylococcal Skin Infections

C. Buddy Creech, Duha N. Al-Zubeidi, Stephanie A. Fritz

Research output: Contribution to journal › Review article › peer-review

59 Scopus citations

Abstract

Staphylococcus aureus infections pose a significant health burden. The emergence of community-associated methicillin-resistant S aureus has resulted in an epidemic of skin and soft tissue infections (SSTI), and many patients experience recurrent SSTI. As S aureus colonization is associated with subsequent infection, decolonization is recommended for patients with recurrent SSTI or in settings of ongoing transmission. S aureus infections often cluster within households, and asymptomatic carriers serve as reservoirs for transmission; therefore, a household approach to decolonization is more effective than measures performed by individuals alone. Novel strategies for the prevention of recurrent SSTI are needed.

Original language	English
Pages (from-to)	429-464
Number of pages	36
Journal	Infectious disease clinics of North America
Volume	29
Issue number	3
DOIs	https://doi.org/10.1016/j.idc.2015.05.007
State	Published - 2015

Keywords

Decolonization
MRSA
Pediatrics
Prevention
Skin infection
Staphylococcal vaccine
Staphylococcus aureus

Access to Document

10.1016/j.idc.2015.05.007

Cite this

@article{3b3f5080ea9d4732a84901f0f7dd2ff1,

title = "Prevention of Recurrent Staphylococcal Skin Infections",

abstract = "Staphylococcus aureus infections pose a significant health burden. The emergence of community-associated methicillin-resistant S aureus has resulted in an epidemic of skin and soft tissue infections (SSTI), and many patients experience recurrent SSTI. As S aureus colonization is associated with subsequent infection, decolonization is recommended for patients with recurrent SSTI or in settings of ongoing transmission. S aureus infections often cluster within households, and asymptomatic carriers serve as reservoirs for transmission; therefore, a household approach to decolonization is more effective than measures performed by individuals alone. Novel strategies for the prevention of recurrent SSTI are needed.",

keywords = "Decolonization, MRSA, Pediatrics, Prevention, Skin infection, Staphylococcal vaccine, Staphylococcus aureus",

author = "Creech, {C. Buddy} and Al-Zubeidi, {Duha N.} and Fritz, {Stephanie A.}",

note = "Funding Information: Disclosure statement: This work was supported by grants from the National Institutes of Health ( K23-AI091690 , KL2-RR024994 , and UL1-TR000448 ), the Agency for Healthcare Research and Quality ( R01-HS021736 ), and the Children{\textquoteright}s Discovery Institute of Washington University and St. Louis Children{\textquoteright}s Hospital (to S.A. Fritz). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health or the Agency for Healthcare Research and Quality. Publisher Copyright: {\textcopyright} 2015 Elsevier Inc..",

year = "2015",

doi = "10.1016/j.idc.2015.05.007",

language = "English",

volume = "29",

pages = "429--464",

journal = "Infectious Disease Clinics of North America",

issn = "0891-5520",

number = "3",

}

TY - JOUR

T1 - Prevention of Recurrent Staphylococcal Skin Infections

AU - Creech, C. Buddy

AU - Al-Zubeidi, Duha N.

AU - Fritz, Stephanie A.

N1 - Funding Information: Disclosure statement: This work was supported by grants from the National Institutes of Health ( K23-AI091690 , KL2-RR024994 , and UL1-TR000448 ), the Agency for Healthcare Research and Quality ( R01-HS021736 ), and the Children’s Discovery Institute of Washington University and St. Louis Children’s Hospital (to S.A. Fritz). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health or the Agency for Healthcare Research and Quality. Publisher Copyright: © 2015 Elsevier Inc..

PY - 2015

Y1 - 2015

N2 - Staphylococcus aureus infections pose a significant health burden. The emergence of community-associated methicillin-resistant S aureus has resulted in an epidemic of skin and soft tissue infections (SSTI), and many patients experience recurrent SSTI. As S aureus colonization is associated with subsequent infection, decolonization is recommended for patients with recurrent SSTI or in settings of ongoing transmission. S aureus infections often cluster within households, and asymptomatic carriers serve as reservoirs for transmission; therefore, a household approach to decolonization is more effective than measures performed by individuals alone. Novel strategies for the prevention of recurrent SSTI are needed.

AB - Staphylococcus aureus infections pose a significant health burden. The emergence of community-associated methicillin-resistant S aureus has resulted in an epidemic of skin and soft tissue infections (SSTI), and many patients experience recurrent SSTI. As S aureus colonization is associated with subsequent infection, decolonization is recommended for patients with recurrent SSTI or in settings of ongoing transmission. S aureus infections often cluster within households, and asymptomatic carriers serve as reservoirs for transmission; therefore, a household approach to decolonization is more effective than measures performed by individuals alone. Novel strategies for the prevention of recurrent SSTI are needed.

KW - Decolonization

KW - MRSA

KW - Pediatrics

KW - Prevention

KW - Skin infection

KW - Staphylococcal vaccine

KW - Staphylococcus aureus

UR - http://www.scopus.com/inward/record.url?scp=84951927011&partnerID=8YFLogxK

U2 - 10.1016/j.idc.2015.05.007

DO - 10.1016/j.idc.2015.05.007

M3 - Review article

C2 - 26311356

AN - SCOPUS:84951927011

SN - 0891-5520

VL - 29

SP - 429

EP - 464

JO - Infectious Disease Clinics of North America

JF - Infectious Disease Clinics of North America

IS - 3

ER -

Prevention of Recurrent Staphylococcal Skin Infections

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this