Prevention of hospital-acquired pneumonia

Patrick G. Lyons, Marin H. Kollef

Research output: Contribution to journalReview articlepeer-review

22 Scopus citations


Purpose of review Hospital-acquired pneumonia (HAP) is the leading cause of death from hospital-acquired infection. Little work has been done on strategies for prevention of HAP. This review aims to describe potential HAP prevention strategies and the evidence supporting them. Oral care and aspiration precautions may attenuate some risk for HAP. Oral and digestive decontamination with antibiotics may be effective but could increase risk for resistant organisms. Other preventive measures, including isolation practices, remain theoretical or experimental. Recent findings Hospital-acquired pneumonia occurs because of pharyngeal colonization with pathogenic organisms and subsequent aspiration of these pathogens. Summary Most potential HAP prevention strategies remain unproven.

Original languageEnglish
Pages (from-to)370-378
Number of pages9
JournalCurrent Opinion in Critical Care
Issue number5
StatePublished - 2018


  • Aspiration
  • Hospital-acquired infections
  • Hospital-acquired pneumonia
  • Oral care
  • Prevention


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