TY - JOUR
T1 - Prevalence of nasopharyngeal pneumococcal colonization in children and antimicrobial susceptibility profiles of carriage isolates
AU - Zhou, Julie Y.
AU - Isaacson-Schmid, Megan
AU - Utterson, Elizabeth C.
AU - Todd, Elizabeth M.
AU - McFarland, Michelle
AU - Sivapalan, Janardan
AU - Niehoff, Joan M.
AU - Burnham, Carey Ann D.
AU - Morley, S. Celeste
N1 - Funding Information:
The authors thank Phillip Tarr, Stephanie Fritz, and Steen Hoffmann for critical review of the manuscript, and Patricia Sellenriek of the SLCH Microbiology Laboratory for advice and assistance. The authors also thank the faculty of the Washington University School of Medicine Department of Surgery and the Same Day Surgery nursing staff of St. Louis Children's Hospital for facilitating the enrollment of patients. Funding for the study was provided by the Children's Discovery Institute in St. Louis (grant numbers PD-II-2013-295 and PD-II-2014-366). S.C.M. is also a Scholar of the Child Health Research Center of Excellence in Developmental Biology at Washington University School of Medicine (grant number K12-HD01487).
Publisher Copyright:
© 2015 The Authors.
PY - 2015/10/1
Y1 - 2015/10/1
N2 - Nasopharyngeal (NP) pneumococcal carriage predisposes children to pneumococcal infections. Defining the proportion of pneumococcal isolates that are antibiotic-resistant enables the appropriate choice of empiric therapies. The antibiogram of NP carriage isolates derived from a pediatric population following the introduction of the 13-valent pneumococcal conjugate vaccine was defined in this study.
AB - Nasopharyngeal (NP) pneumococcal carriage predisposes children to pneumococcal infections. Defining the proportion of pneumococcal isolates that are antibiotic-resistant enables the appropriate choice of empiric therapies. The antibiogram of NP carriage isolates derived from a pediatric population following the introduction of the 13-valent pneumococcal conjugate vaccine was defined in this study.
KW - Antimicrobial resistance
KW - Colonization
KW - Epidemiology
KW - Streptococcus pneumoniae
UR - http://www.scopus.com/inward/record.url?scp=84941947159&partnerID=8YFLogxK
U2 - 10.1016/j.ijid.2015.08.010
DO - 10.1016/j.ijid.2015.08.010
M3 - Article
C2 - 26327122
AN - SCOPUS:84941947159
SN - 1201-9712
VL - 39
SP - 50
EP - 52
JO - International Journal of Infectious Diseases
JF - International Journal of Infectious Diseases
ER -