Presumed parvovirus B19-associated retinal pigment epitheliopathy

M. Gilbert Grand, Gregory A. Storch

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Purpose: To describe a patient with a white dot syndrome associated with acute erythema infectiosum. Methods: A patient with a clinical history of erythema infectiosum and multifocal punctate white lesions at the level of the retinal pigment epithelium was followed up for an 8-month interval. Serum was tested for immunoglobulin M (IgM) and IgG antibodies to parvovirus B19 at the time of the initial evaluation and during convalescence using an indirect immunofluorescence antibody technique. Serial photographs and fluorescein angiograms were obtained. Results: IgM and IgG antibodies to parvovirus were detected in the serum at the time of initial evaluation; IgM antibodies had disappeared but IgG antibodies persisted in serum obtained at 1-month follow- up. Fundus evaluation revealed clinical disappearance of some lesions, with increased pigmentation of others over the course of follow-up. Conclusion: The authors have identified an adult patient who presented with a white dot syndrome associated with acute erythema infectiosum documented by serologically proved parvovirus B19 infection.

Original languageEnglish
Pages (from-to)199-202
Number of pages4
Issue number2
StatePublished - 2000


  • Erythema infectiosum
  • Parvovirus
  • Retinal pigment epitheliopathy
  • White dot syndrome


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