Presence of the KPC carbapenemase gene in enterobacteriaceae causing bacteremia and its correlation with in vitro carbapenem susceptibility

Jonas Marschall; Robert J. Tibbetts; W. Michael Dunne; Jonathan G. Frye; Victoria J. Fraser; David K. Warren

doi:10.1128/JCM.02123-08

Presence of the KPC carbapenemase gene in enterobacteriaceae causing bacteremia and its correlation with in vitro carbapenem susceptibility

Jonas Marschall
, Robert J. Tibbetts
, W. Michael Dunne
, Jonathan G. Frye
, Victoria J. Fraser
, David K. Warren

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

During 6 months, we obtained Enterobacteriaceae isolates from patients with gram-negative bacteremia at a 1,250-bed teaching hospital in St. Louis, MO, and compared carbapenem susceptibilities with the presence of bla _KPC, a transferable carbapenemase gene. Three (1.2%) out of 243 isolates were bla _KPC positive. Ertapenem nonsusceptibility had a low positive predictive value.

Original language	English
Pages (from-to)	239-241
Number of pages	3
Journal	Journal of clinical microbiology
Volume	47
Issue number	1
DOIs	https://doi.org/10.1128/JCM.02123-08
State	Published - Jan 2009

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abstract = "During 6 months, we obtained Enterobacteriaceae isolates from patients with gram-negative bacteremia at a 1,250-bed teaching hospital in St. Louis, MO, and compared carbapenem susceptibilities with the presence of bla KPC, a transferable carbapenemase gene. Three (1.2\%) out of 243 isolates were bla KPC positive. Ertapenem nonsusceptibility had a low positive predictive value.",

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AU - Marschall, Jonas

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AU - Frye, Jonathan G.

AU - Fraser, Victoria J.

AU - Warren, David K.

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AB - During 6 months, we obtained Enterobacteriaceae isolates from patients with gram-negative bacteremia at a 1,250-bed teaching hospital in St. Louis, MO, and compared carbapenem susceptibilities with the presence of bla KPC, a transferable carbapenemase gene. Three (1.2%) out of 243 isolates were bla KPC positive. Ertapenem nonsusceptibility had a low positive predictive value.

UR - https://www.scopus.com/pages/publications/58849115530

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AN - SCOPUS:58849115530

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Presence of the KPC carbapenemase gene in enterobacteriaceae causing bacteremia and its correlation with in vitro carbapenem susceptibility

Abstract

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