Preparation and properties of phosphomannomutase from baker's yeast

Luis Glaser; Stuart Kornfeld; David H. Brown

doi:10.1016/0006-3002(59)90143-X

Preparation and properties of phosphomannomutase from baker's yeast

Luis Glaser
, Stuart Kornfeld
, David H. Brown

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

A partially purified yeast enzyme is described which catalyzes specifically the conversion of α-mannose-1-phosphate to mannos-6-phosphate. This enzyme has been named phosphomannomutase. The enzyme is inactive in the absence of α-glucose-1,6-diphosphate or α-mannose-1,6-diphosphate. The apparent Michaelis constant of either coenzyme is approximately 1.5·10^-4 M. Evidence is presented that phosphomannomutase is distinct from phosphoglucomutase.

Original language	English
Pages (from-to)	522-526
Number of pages	5
Journal	BBA - Biochimica et Biophysica Acta
Volume	33
Issue number	2
DOIs	https://doi.org/10.1016/0006-3002(59)90143-X
State	Published - Jun 1959

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title = "Preparation and properties of phosphomannomutase from baker's yeast",

abstract = "A partially purified yeast enzyme is described which catalyzes specifically the conversion of α-mannose-1-phosphate to mannos-6-phosphate. This enzyme has been named phosphomannomutase. The enzyme is inactive in the absence of α-glucose-1,6-diphosphate or α-mannose-1,6-diphosphate. The apparent Michaelis constant of either coenzyme is approximately 1.5·10-4 M. Evidence is presented that phosphomannomutase is distinct from phosphoglucomutase.",

author = "Luis Glaser and Stuart Kornfeld and Brown, \{David H.\}",

note = "Funding Information: Supported by a grant (RG-476I) from the National Institutes of Health, U. S. Public Health Service. L.G. is a Research Fellow of the Helen Hay Whitney Foundation.",

year = "1959",

month = jun,

doi = "10.1016/0006-3002(59)90143-X",

language = "English",

volume = "33",

pages = "522--526",

journal = "BBA - Biochimica et Biophysica Acta",

issn = "0006-3002",

number = "2",

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TY - JOUR

T1 - Preparation and properties of phosphomannomutase from baker's yeast

AU - Glaser, Luis

AU - Kornfeld, Stuart

AU - Brown, David H.

N1 - Funding Information: Supported by a grant (RG-476I) from the National Institutes of Health, U. S. Public Health Service. L.G. is a Research Fellow of the Helen Hay Whitney Foundation.

PY - 1959/6

Y1 - 1959/6

N2 - A partially purified yeast enzyme is described which catalyzes specifically the conversion of α-mannose-1-phosphate to mannos-6-phosphate. This enzyme has been named phosphomannomutase. The enzyme is inactive in the absence of α-glucose-1,6-diphosphate or α-mannose-1,6-diphosphate. The apparent Michaelis constant of either coenzyme is approximately 1.5·10-4 M. Evidence is presented that phosphomannomutase is distinct from phosphoglucomutase.

AB - A partially purified yeast enzyme is described which catalyzes specifically the conversion of α-mannose-1-phosphate to mannos-6-phosphate. This enzyme has been named phosphomannomutase. The enzyme is inactive in the absence of α-glucose-1,6-diphosphate or α-mannose-1,6-diphosphate. The apparent Michaelis constant of either coenzyme is approximately 1.5·10-4 M. Evidence is presented that phosphomannomutase is distinct from phosphoglucomutase.

UR - https://www.scopus.com/pages/publications/0000127730

U2 - 10.1016/0006-3002(59)90143-X

DO - 10.1016/0006-3002(59)90143-X

M3 - Article

C2 - 13670924

AN - SCOPUS:0000127730

SN - 0006-3002

VL - 33

SP - 522

EP - 526

JO - BBA - Biochimica et Biophysica Acta

JF - BBA - Biochimica et Biophysica Acta

IS - 2

ER -

Preparation and properties of phosphomannomutase from baker's yeast

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