TY - JOUR
T1 - Preparation and properties of phosphomannomutase from baker's yeast
AU - Glaser, Luis
AU - Kornfeld, Stuart
AU - Brown, David H.
N1 - Funding Information:
Supported by a grant (RG-476I) from the National Institutes of Health, U. S. Public Health Service. L.G. is a Research Fellow of the Helen Hay Whitney Foundation.
PY - 1959/6
Y1 - 1959/6
N2 - A partially purified yeast enzyme is described which catalyzes specifically the conversion of α-mannose-1-phosphate to mannos-6-phosphate. This enzyme has been named phosphomannomutase. The enzyme is inactive in the absence of α-glucose-1,6-diphosphate or α-mannose-1,6-diphosphate. The apparent Michaelis constant of either coenzyme is approximately 1.5·10-4 M. Evidence is presented that phosphomannomutase is distinct from phosphoglucomutase.
AB - A partially purified yeast enzyme is described which catalyzes specifically the conversion of α-mannose-1-phosphate to mannos-6-phosphate. This enzyme has been named phosphomannomutase. The enzyme is inactive in the absence of α-glucose-1,6-diphosphate or α-mannose-1,6-diphosphate. The apparent Michaelis constant of either coenzyme is approximately 1.5·10-4 M. Evidence is presented that phosphomannomutase is distinct from phosphoglucomutase.
UR - http://www.scopus.com/inward/record.url?scp=0000127730&partnerID=8YFLogxK
U2 - 10.1016/0006-3002(59)90143-X
DO - 10.1016/0006-3002(59)90143-X
M3 - Article
C2 - 13670924
AN - SCOPUS:0000127730
SN - 0006-3002
VL - 33
SP - 522
EP - 526
JO - BBA - Biochimica et Biophysica Acta
JF - BBA - Biochimica et Biophysica Acta
IS - 2
ER -