Preparation and alkylation of N-t-butyldimethylsilyl-3- trimethylsilyloxyazetidin-2-one

Roland E. Dolle; Mark J. Hughes; Chun Sing Li; Lawrence I. Kruse

doi:10.1039/C39890001448

Preparation and alkylation of N-t-butyldimethylsilyl-3- trimethylsilyloxyazetidin-2-one

Roland E. Dolle
, Mark J. Hughes
, Chun Sing Li
, Lawrence I. Kruse

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

The title β-lactam (6) is prepared in three steps from commercially available 2-azetidinone (9) (50% overall yield) and can be efficiently alkylated with a variety of electrophiles.

Original language	English
Pages (from-to)	1448-1449
Number of pages	2
Journal	Journal of the Chemical Society, Chemical Communications
Issue number	19
DOIs	https://doi.org/10.1039/C39890001448
State	Published - 1989

Access to Document

10.1039/C39890001448

Cite this

@article{cc5a0600f08544f894d713dab2b089e8,

title = "Preparation and alkylation of N-t-butyldimethylsilyl-3- trimethylsilyloxyazetidin-2-one",

abstract = "The title β-lactam (6) is prepared in three steps from commercially available 2-azetidinone (9) (50\% overall yield) and can be efficiently alkylated with a variety of electrophiles.",

author = "Dolle, \{Roland E.\} and Hughes, \{Mark J.\} and Li, \{Chun Sing\} and Kruse, \{Lawrence I.\}",

year = "1989",

doi = "10.1039/C39890001448",

language = "English",

pages = "1448--1449",

journal = "Journal of the Chemical Society, Chemical Communications",

issn = "0022-4936",

number = "19",

}

TY - JOUR

T1 - Preparation and alkylation of N-t-butyldimethylsilyl-3- trimethylsilyloxyazetidin-2-one

AU - Dolle, Roland E.

AU - Hughes, Mark J.

AU - Li, Chun Sing

AU - Kruse, Lawrence I.

PY - 1989

Y1 - 1989

N2 - The title β-lactam (6) is prepared in three steps from commercially available 2-azetidinone (9) (50% overall yield) and can be efficiently alkylated with a variety of electrophiles.

AB - The title β-lactam (6) is prepared in three steps from commercially available 2-azetidinone (9) (50% overall yield) and can be efficiently alkylated with a variety of electrophiles.

UR - https://www.scopus.com/pages/publications/37049085052

U2 - 10.1039/C39890001448

DO - 10.1039/C39890001448

M3 - Article

AN - SCOPUS:37049085052

SN - 0022-4936

SP - 1448

EP - 1449

JO - Journal of the Chemical Society, Chemical Communications

JF - Journal of the Chemical Society, Chemical Communications

IS - 19

ER -

Preparation and alkylation of N-t-butyldimethylsilyl-3- trimethylsilyloxyazetidin-2-one

Abstract

Access to Document

Other files and links

Fingerprint

Cite this