Preparation and alkylation of N-t-butyldimethylsilyl-3- trimethylsilyloxyazetidin-2-one

Roland E. Dolle, Mark J. Hughes, Chun Sing Li, Lawrence I. Kruse

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


The title β-lactam (6) is prepared in three steps from commercially available 2-azetidinone (9) (50% overall yield) and can be efficiently alkylated with a variety of electrophiles.

Original languageEnglish
Pages (from-to)1448-1449
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number19
StatePublished - 1989


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