TY - JOUR
T1 - Preoperative Falls Predict Postoperative Falls, Functional Decline, and Surgical Complications
AU - Kronzer, Vanessa L.
AU - Jerry, Michelle R.
AU - Ben Abdallah, Arbi
AU - Wildes, Troy S.
AU - Stark, Susan L.
AU - McKinnon, Sherry L.
AU - Helsten, Daniel L.
AU - Sharma, Anshuman
AU - Avidan, Michael S.
N1 - Funding Information:
This study was supported by the Institute of Clinical and Translational Sciences grant UL1TR000448 (sub award TL1 TR000449 ) from the National Center for Advancing Translational Sciences , along with grant 1UH2AG050312-01 from the National Institute on Aging , of the National Institutes of Health (NIH, Bethesda, MD, USA). The content is solely the responsibility of the authors and does not necessarily represent the official view of the NIH. It was also supported by grant BJHF#7937-77 from the Barnes-Jewish Hospital Foundation and the Washington University in St. Louis Department of Anesthesiology (Saint Louis, MO, USA). The funding sources had no role in the design or conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; or decision to submit the manuscript for publication.
Publisher Copyright:
© 2016 The Authors
PY - 2016/10/1
Y1 - 2016/10/1
N2 - Background Falls are common and linked to morbidity. Our objectives were to characterize postoperative falls, and determine whether preoperative falls independently predicted postoperative falls (primary outcome), functional dependence, quality of life, complications, and readmission. Methods This prospective cohort study included 7982 unselected patients undergoing elective surgery. Data were collected from the medical record, a baseline survey, and follow-up surveys approximately 30 days and one year after surgery. Results Fall rates (per 100 person-years) peaked at 175 (hospitalization), declined to 140 (30-day survey), and then to 97 (one-year survey). After controlling for confounders, a history of one, two, and ≥ three preoperative falls predicted postoperative falls at 30 days (adjusted odds ratios [aOR] 2.3, 3.6, 5.5) and one year (aOR 2.3, 3.4, 6.9). One, two, and ≥ three falls predicted functional decline at 30 days (aOR 1.2, 2.4, 2.4) and one year (aOR 1.3, 1.5, 3.2), along with in-hospital complications (aOR 1.2, 1.3, 2.0). Fall history predicted adverse outcomes better than commonly-used metrics, but did not predict quality of life deterioration or readmission. Conclusions Falls are common after surgery, and preoperative falls herald postoperative falls and other adverse outcomes. A history of preoperative falls should be routinely ascertained.
AB - Background Falls are common and linked to morbidity. Our objectives were to characterize postoperative falls, and determine whether preoperative falls independently predicted postoperative falls (primary outcome), functional dependence, quality of life, complications, and readmission. Methods This prospective cohort study included 7982 unselected patients undergoing elective surgery. Data were collected from the medical record, a baseline survey, and follow-up surveys approximately 30 days and one year after surgery. Results Fall rates (per 100 person-years) peaked at 175 (hospitalization), declined to 140 (30-day survey), and then to 97 (one-year survey). After controlling for confounders, a history of one, two, and ≥ three preoperative falls predicted postoperative falls at 30 days (adjusted odds ratios [aOR] 2.3, 3.6, 5.5) and one year (aOR 2.3, 3.4, 6.9). One, two, and ≥ three falls predicted functional decline at 30 days (aOR 1.2, 2.4, 2.4) and one year (aOR 1.3, 1.5, 3.2), along with in-hospital complications (aOR 1.2, 1.3, 2.0). Fall history predicted adverse outcomes better than commonly-used metrics, but did not predict quality of life deterioration or readmission. Conclusions Falls are common after surgery, and preoperative falls herald postoperative falls and other adverse outcomes. A history of preoperative falls should be routinely ascertained.
KW - Accidental falls
KW - Elective surgical procedures
KW - Outcome assessment
KW - Patient-reported outcomes
KW - Postoperative period
KW - Preoperative period
UR - http://www.scopus.com/inward/record.url?scp=84992560005&partnerID=8YFLogxK
U2 - 10.1016/j.ebiom.2016.08.039
DO - 10.1016/j.ebiom.2016.08.039
M3 - Article
C2 - 27599969
AN - SCOPUS:84992560005
SN - 2352-3964
VL - 12
SP - 302
EP - 308
JO - EBioMedicine
JF - EBioMedicine
ER -