TY - JOUR
T1 - Preoperative characteristics are associated with increased likelihood of low early postoperative mobility after adult spinal deformity surgery
AU - Schmerler, Jessica
AU - Mo, Kevin C.
AU - Olson, Jarod
AU - Kurian, Shyam J.
AU - Skolasky, Richard L.
AU - Kebaish, Khaled M.
AU - Neuman, Brian J.
N1 - Funding Information:
The study received approval from our institutional review board. IRB committee: IRB-X, IRB number: IRB00135145. For editorial assistance, we thank Denise Di Salvo, MS, and Rachel Box, MS, in the Editorial Services group of The Johns Hopkins Department of Orthopaedic Surgery. Author disclosures: JS: Nothing to disclose. KCM: Nothing to disclose. JO: Nothing to disclose. SJK: Nothing to disclose. RLS: Grants: PCORI (Paid directly to institution), Grants: NIA (Paid directly to institution); Research Support (Investigator Salary): PCORI (Paid directly to institution), Research Support (Investigator Salary): NIA (Paid directly to institution); Research Support (Staff and/or Materials): PCORI (Paid directly to institution), Research Support (Staff and/or Materials): NIA (Paid directly to institution); Board of Directors: North American Spine Society (Nonfinancial); Board of Directors: International Society for Quality of Life Research (Nonfinancial); Scientific Advisory Board: Quality of Life Research, Co-Editor in Chief (B); KMK: Royalties: Depuy Synthes (F), Royalties: Stryker (F), Royalties: Orthofix (D), Royalties: SpineCraft (C), Consulting: Depuy Synthes (D). BJN: Speaking and/or Teaching arrangements: Baxter (B).
Publisher Copyright:
© 2022 Elsevier Inc.
PY - 2022
Y1 - 2022
N2 - BACKGROUND CONTEXT: Low early postoperative mobility (LEPOM) has been shown to be associated with increased length of hospital stay, complication rates, and likelihood of nonhome discharge. However, few studies have examined preoperative characteristics associated with LEPOM in adult spinal deformity (ASD) patients. PURPOSE: To investigate which preoperative patient characteristics may be associated with LEPOM after ASD surgery. DESIGN: Retrospective review. PATIENT SAMPLE: Included were 86 ASD patients with fusion of ≥5 levels for whom immediate-postoperative AM-PAC Basic Mobility Inpatient Short Form (6-Clicks) scores had been obtained. OUTCOME MEASURES: The primary outcome of this study was the likelihood of LEPOM, defined as an AM-PAC score ≤15, which is associated with inability to stand for more than 1 minute. METHODS: Significant cutoffs for preoperative characteristics associated with LEPOM were determined via threshold linear regression. Multivariable logistic regression was used to assess the impact of preoperative characteristics on the likelihood of LEPOM. RESULTS: LEPOM was recorded in 38 patients (44.2%). Threshold regression identified the following cutoffs to be associated with LEPOM: preoperative Patient Reported Outcomes Measurement Information System (PROMIS) scores of ≥68 for Pain, <28.3 for Physical Function, and ≥63.4 for Anxiety; preoperative Oswestry disability index (ODI) score of ≥60; and body mass index (BMI) of ≥35.2. On multivariate analysis, preoperative PROMIS scores of ≥68 for Pain (odds ratio [OR] 5.3, confidence interval [CI] 1.2–22.8, p=.03), <28.3 for Physical Function (OR 10.1, CI 1.8–58.2, p=.01), and ≥63.4 for Anxiety (OR 4.7, CI 1.1–20.8, p=.04); preoperative ODI score ≥60 (OR 38.8, CI 4.0–373.6, p=.002); BMI ≥35.2 (OR 14.2, CI 1.3–160.0, p=.03), and male sex (OR 5.4, CI 1.2–23.7, p=.03) were associated with increased odds of LEPOM. CONCLUSIONS: Preoperative PROMIS Pain, Physical Function, and Anxiety scores; ODI score; BMI; and male sex were associated with LEPOM. Several of these characteristics are modifiable risk factors and thus may be candidates for optimization before surgery.
AB - BACKGROUND CONTEXT: Low early postoperative mobility (LEPOM) has been shown to be associated with increased length of hospital stay, complication rates, and likelihood of nonhome discharge. However, few studies have examined preoperative characteristics associated with LEPOM in adult spinal deformity (ASD) patients. PURPOSE: To investigate which preoperative patient characteristics may be associated with LEPOM after ASD surgery. DESIGN: Retrospective review. PATIENT SAMPLE: Included were 86 ASD patients with fusion of ≥5 levels for whom immediate-postoperative AM-PAC Basic Mobility Inpatient Short Form (6-Clicks) scores had been obtained. OUTCOME MEASURES: The primary outcome of this study was the likelihood of LEPOM, defined as an AM-PAC score ≤15, which is associated with inability to stand for more than 1 minute. METHODS: Significant cutoffs for preoperative characteristics associated with LEPOM were determined via threshold linear regression. Multivariable logistic regression was used to assess the impact of preoperative characteristics on the likelihood of LEPOM. RESULTS: LEPOM was recorded in 38 patients (44.2%). Threshold regression identified the following cutoffs to be associated with LEPOM: preoperative Patient Reported Outcomes Measurement Information System (PROMIS) scores of ≥68 for Pain, <28.3 for Physical Function, and ≥63.4 for Anxiety; preoperative Oswestry disability index (ODI) score of ≥60; and body mass index (BMI) of ≥35.2. On multivariate analysis, preoperative PROMIS scores of ≥68 for Pain (odds ratio [OR] 5.3, confidence interval [CI] 1.2–22.8, p=.03), <28.3 for Physical Function (OR 10.1, CI 1.8–58.2, p=.01), and ≥63.4 for Anxiety (OR 4.7, CI 1.1–20.8, p=.04); preoperative ODI score ≥60 (OR 38.8, CI 4.0–373.6, p=.002); BMI ≥35.2 (OR 14.2, CI 1.3–160.0, p=.03), and male sex (OR 5.4, CI 1.2–23.7, p=.03) were associated with increased odds of LEPOM. CONCLUSIONS: Preoperative PROMIS Pain, Physical Function, and Anxiety scores; ODI score; BMI; and male sex were associated with LEPOM. Several of these characteristics are modifiable risk factors and thus may be candidates for optimization before surgery.
KW - AM-PAC
KW - Adult spinal deformity
KW - Dependent ambulation
KW - Health planning guidelines
KW - Health-care costs
KW - Mobility
KW - Needs assessment
KW - Pain
KW - Threshold regression
KW - Walking
UR - http://www.scopus.com/inward/record.url?scp=85147013813&partnerID=8YFLogxK
U2 - 10.1016/j.spinee.2022.12.004
DO - 10.1016/j.spinee.2022.12.004
M3 - Article
C2 - 36509380
AN - SCOPUS:85147013813
SN - 1529-9430
JO - Spine Journal
JF - Spine Journal
ER -