Preliminary results from a portable PET probe system with fast image reconstruction

Ke Li, Aswin Mathews, Qiang Wang, Jie Wen, Joseph A. O'Sullivan, Yuan Chuan Tai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We are developing a Point-Of-Care PET (POC-PET) imaging system platform that consists of one or more movable probe detectors in coincidence with a detector-array behind a patient. The probes are hand movable so that the operator can control the probe trajectory freely to achieve optimal coverage and sensitivity for patient-specific imaging tasks. This platform does not require a conventional full ring geometry, and as such it can be built portable and low cost for bed-side or intraoperative imaging. We developed a prototype that consists of a compact high resolution MPPC detector probe and a half ring of conventional detectors. The probe detector has 20×20 crystals of 0.74×0.74×3.0 mm3 each, in 0.8 mm pitches, read out by a MPPC array. The probe is fixed to a Microscribe device, which tracks the location and orientation of the probe in 3D space as it moves. A fully 3D list-mode TOF (Time-Of-Flight) image reconstruction algorithm has been developed to incorporate the dynamically changing geometry information acquired from the Microscribe. The algorithm is implemented on GPU to achieve fast reconstruction in the order of seconds, under practical count rate situations. Further Monte Carlo simulations show that the resolvability of 4 mm rods under practical contrast ratio could be achieved if the scanning trajectory is well designed.

Original languageEnglish
Title of host publication2014 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781479960972
DOIs
StatePublished - Mar 10 2016
EventIEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2014 - Seattle, United States
Duration: Nov 8 2014Nov 15 2014

Publication series

Name2014 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2014

Conference

ConferenceIEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2014
CountryUnited States
CitySeattle
Period11/8/1411/15/14

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  • Cite this

    Li, K., Mathews, A., Wang, Q., Wen, J., O'Sullivan, J. A., & Tai, Y. C. (2016). Preliminary results from a portable PET probe system with fast image reconstruction. In 2014 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2014 [7430751] (2014 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2014). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NSSMIC.2014.7430751