Abstract
Image-based computational models have been used by many researchers to quantify mechanical stress/strain conditions and flow wall shear stress and try to use them to understand mechanisms governing vulnerable plaque progression and rupture processes. In this chapter, we will focus on human coronary plaque modeling efforts based on in vivo imaging data, including image preparation, 3D reconstruction, residual stress, vessel zero-load geometry, in vivo vessel material properties, plaque progression prediction, and plaque vulnerability change prediction based on patient follow-up data. Imaging and modeling limitations and challenges will also be discussed.
Original language | English |
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Title of host publication | Biomechanics of Coronary Atherosclerotic Plaque |
Subtitle of host publication | From Model to Patient |
Publisher | Elsevier |
Pages | 315-333 |
Number of pages | 19 |
ISBN (Electronic) | 9780128171950 |
ISBN (Print) | 9780128171967 |
DOIs | |
State | Published - Jan 1 2021 |
Keywords
- Coronary
- Plaque mechanical analysis
- Plaque progression
- Plaque rupture
- Plaque vulnerability
- Progression prediction
- Vulnerable plaque