Abstract
Estimated glomerular filtration rate and albuminuria are dominant clinical predictors of renal outcomes in chronic kidney disease. Wong and collaborators report that BMP-7 and transforming growth factor-β1 improve risk discrimination for renal end points in type 2 diabetes. However, to develop predictive models, clearly defined, clinically meaningful, validated end points must be used. End-stage renal disease and kidney transplantation remain the most definitive renal end points, whereas doubling of serum creatinine and death from renal disease lack rigor.
| Original language | English |
|---|---|
| Pages (from-to) | 189-191 |
| Number of pages | 3 |
| Journal | Kidney International |
| Volume | 83 |
| Issue number | 2 |
| DOIs |
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| State | Published - Feb 2013 |