Accurate prediction of the complete structures of protein-coding genes, including 5′-untranslated regions, is crucial for full interpretation of genome sequence. A new report describes the statistical properties of the first exons of genes, and presents a novel statistical method for predicting their boundaries. First exons, which are partially or completely non-coding, have been relatively neglected by gene-finding algorithms. When integrated with other genome annotation tools, this new method will improve the technology of automated genome interpretation.

Original languageEnglish
Pages (from-to)273-275
Number of pages3
JournalTrends in Biotechnology
Issue number7
StatePublished - Jul 1 2002


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