Predicting Conversion to Dementia of the Alzheimer's Type in a Healthy Control Sample: The Power of Errors in Stroop Color Naming

David A. Balota, Chi Shing Tse, Keith A. Hutchison, Daniel H. Spieler, Janet M. Duchek, John C. Morris

Research output: Contribution to journalArticle

75 Scopus citations

Abstract

In the present study, we investigated which cognitive functions in older adults at Time A are predictive of conversion to dementia of the Alzheimer's type (DAT) at Time B. Forty-seven healthy individuals were initially tested in 1992-1994 on a trial-by-trial computerized Stroop task along with a battery of psychometric measures that tap general knowledge, declarative memory, visual-spatial processing, and processing speed. Twelve of these individuals subsequently developed DAT. The errors on the color incongruent trials (along with the difference between congruent and incongruent trials) and changes in the reaction time distributions were the strongest predictors of conversion to DAT, consistent with recent arguments regarding the sensitivity of these measures. Notably in the psychometric measures, there was little evidence of a difference in declarative memory between converters and nonconverters, but there was some evidence of changes in visual-spatial processing. Discussion focuses on the accumulating evidence suggesting a role of attentional control mechanisms as an early marker for the transition from healthy cognitive aging to DAT.

Original languageEnglish
Pages (from-to)208-218
Number of pages11
JournalPsychology and Aging
Volume25
Issue number1
DOIs
StatePublished - Mar 1 2010
Externally publishedYes

Keywords

  • Alzheimer's disease
  • Attentional control
  • Conversion
  • Dementia
  • Stroop

Fingerprint Dive into the research topics of 'Predicting Conversion to Dementia of the Alzheimer's Type in a Healthy Control Sample: The Power of Errors in Stroop Color Naming'. Together they form a unique fingerprint.

  • Cite this