Practical Clinical Workflows for Online and Offline Adaptive Radiation Therapy

Olga L. Green, Lauren E. Henke, Geoffrey D. Hugo

Research output: Contribution to journalArticlepeer-review

89 Scopus citations


Adaptive radiotherapy emerged over 20 years ago and is now an established clinical practice in a number of organ sites. No one solution for adaptive therapy exists. Rather, adaptive radiotherapy is a process which combines multiple tools for imaging, assessment of need for adaptation, treatment planning, and quality assurance of this process. Workflow is therefore a critical aspect to ensure safe, effective, and efficient implementation of adaptive radiotherapy. In this work, we discuss the tools for online and offline adaptive radiotherapy and introduce workflow concepts for these types of adaptive radiotherapy. Common themes and differences between the workflows are introduced and controversies and areas of active research are discussed.

Original languageEnglish
Pages (from-to)219-227
Number of pages9
JournalSeminars in Radiation Oncology
Issue number3
StatePublished - Jul 2019


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