Powassan Virus Infection Detected by Metagenomic Next-Generation Sequencing, Ohio, USA

Marjorie Farrington; Jamie Elenz; Matthew Ginsberg; Charles Chiu; Steve Miller; Scott F. Pangonis

doi:10.3201/eid2904.221005

Powassan Virus Infection Detected by Metagenomic Next-Generation Sequencing, Ohio, USA

Marjorie Farrington
, Jamie Elenz
, Matthew Ginsberg
, Charles Chiu
, Steve Miller
, Scott F. Pangonis

Division of Hospital Medicine

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

We describe a 4-year-old male patient in Ohio, USA, who had encephalitis caused by Powassan virus lineage 2. Virus was detected by using metagenomic next-generation sequencing and confirmed with IgM and plaque reduction neutralization assays. Clinicians should recognize changing epidemiology of tickborne viruses to enhance encephalitis diagnosis and management.

Original language	English
Pages (from-to)	838-841
Number of pages	4
Journal	Emerging Infectious Diseases
Volume	29
Issue number	4
DOIs	https://doi.org/10.3201/eid2904.221005
State	Published - Apr 2023

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10.3201/eid2904.221005

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@article{f56b83ab69f44f0fbb98df0e405384cc,

title = "Powassan Virus Infection Detected by Metagenomic Next-Generation Sequencing, Ohio, USA",

abstract = "We describe a 4-year-old male patient in Ohio, USA, who had encephalitis caused by Powassan virus lineage 2. Virus was detected by using metagenomic next-generation sequencing and confirmed with IgM and plaque reduction neutralization assays. Clinicians should recognize changing epidemiology of tickborne viruses to enhance encephalitis diagnosis and management.",

author = "Marjorie Farrington and Jamie Elenz and Matthew Ginsberg and Charles Chiu and Steve Miller and Pangonis, \{Scott F.\}",

year = "2023",

month = apr,

doi = "10.3201/eid2904.221005",

language = "English",

volume = "29",

pages = "838--841",

journal = "Emerging Infectious Diseases",

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T1 - Powassan Virus Infection Detected by Metagenomic Next-Generation Sequencing, Ohio, USA

AU - Farrington, Marjorie

AU - Elenz, Jamie

AU - Ginsberg, Matthew

AU - Chiu, Charles

AU - Miller, Steve

AU - Pangonis, Scott F.

PY - 2023/4

Y1 - 2023/4

N2 - We describe a 4-year-old male patient in Ohio, USA, who had encephalitis caused by Powassan virus lineage 2. Virus was detected by using metagenomic next-generation sequencing and confirmed with IgM and plaque reduction neutralization assays. Clinicians should recognize changing epidemiology of tickborne viruses to enhance encephalitis diagnosis and management.

AB - We describe a 4-year-old male patient in Ohio, USA, who had encephalitis caused by Powassan virus lineage 2. Virus was detected by using metagenomic next-generation sequencing and confirmed with IgM and plaque reduction neutralization assays. Clinicians should recognize changing epidemiology of tickborne viruses to enhance encephalitis diagnosis and management.

UR - https://www.scopus.com/pages/publications/85150807618

U2 - 10.3201/eid2904.221005

DO - 10.3201/eid2904.221005

M3 - Article

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AN - SCOPUS:85150807618

SN - 1080-6040

VL - 29

SP - 838

EP - 841

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

IS - 4

ER -

Powassan Virus Infection Detected by Metagenomic Next-Generation Sequencing, Ohio, USA

Abstract

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