TY - JOUR
T1 - Postoperative surveillance of small appendiceal carcinoid tumors
AU - Murray, Sara E.
AU - Lloyd, Ricardo V.
AU - Sippel, Rebecca S.
AU - Chen, Herbert
AU - Oltmann, Sarah C.
N1 - Funding Information:
This study was supported by grant T32 CA009614-21 from the National Institutes of Health (Bethesda, MD), University of Wisconsin, Physician Scientist Training in Career Medicine.
PY - 2014/3
Y1 - 2014/3
N2 - Background The necessity and frequency of postoperative surveillance for appendiceal carcinoid tumors ≤1 cm are undetermined. Methods A retrospective review was conducted of all patients with appendiceal carcinoid tumors ≤1 cm managed at an academic, tertiary referral center. Clinicopathologic characteristics, treatment, surveillance, recurrence, and survival were assessed and analyzed. Results Over a 16-year period, 31 patients met the inclusion criteria. Appendicitis (n = 17) and pelvic mass (n = 5) were the most common presentations. Median tumor diameter was 5 mm (range, 1-10 mm). Two patients had mesoappendiceal involvement. No patients had regional lymph node involvement or distant metastasis. Postoperatively, 14 patients (45%) received follow-up recommendations, including ≥1 of the following: imaging (n = 9), medical oncology referral (n = 7), colonoscopy (n = 5), and laboratory studies (n = 5). There were no recurrences or disease-specific deaths during a median follow-up period of 5 years (range, 0-15 years). Conclusions Appendiceal carcinoids ≤1 cm are unlikely to recur. Therefore, postoperative surveillance may be unnecessary.
AB - Background The necessity and frequency of postoperative surveillance for appendiceal carcinoid tumors ≤1 cm are undetermined. Methods A retrospective review was conducted of all patients with appendiceal carcinoid tumors ≤1 cm managed at an academic, tertiary referral center. Clinicopathologic characteristics, treatment, surveillance, recurrence, and survival were assessed and analyzed. Results Over a 16-year period, 31 patients met the inclusion criteria. Appendicitis (n = 17) and pelvic mass (n = 5) were the most common presentations. Median tumor diameter was 5 mm (range, 1-10 mm). Two patients had mesoappendiceal involvement. No patients had regional lymph node involvement or distant metastasis. Postoperatively, 14 patients (45%) received follow-up recommendations, including ≥1 of the following: imaging (n = 9), medical oncology referral (n = 7), colonoscopy (n = 5), and laboratory studies (n = 5). There were no recurrences or disease-specific deaths during a median follow-up period of 5 years (range, 0-15 years). Conclusions Appendiceal carcinoids ≤1 cm are unlikely to recur. Therefore, postoperative surveillance may be unnecessary.
KW - Appendix
KW - Carcinoid
KW - Follow-up
KW - Recommendation
KW - Surveillance
KW - Tumor
UR - http://www.scopus.com/inward/record.url?scp=84895466507&partnerID=8YFLogxK
U2 - 10.1016/j.amjsurg.2013.08.038
DO - 10.1016/j.amjsurg.2013.08.038
M3 - Article
C2 - 24393285
AN - SCOPUS:84895466507
SN - 0002-9610
VL - 207
SP - 342
EP - 345
JO - American journal of surgery
JF - American journal of surgery
IS - 3
ER -