Posterior Reversible Encephalopathy Syndrome

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Abstract

Posterior reversible encephalopathy syndrome (PRES) is characterized by headache, altered consciousness, visual disturbances, and seizures, along with distinctive findings on MRI. Conditions particularly associated with the disorder include hypertensive emergency, preeclampsia/eclampsia, posttransplantation status, and chemotherapy for malignancy. MRI is the imaging modality of choice for assisting in the diagnosis of PRES. Treatment includes aggressive blood pressure reduction in most cases, along with reversal of the underlying predisposing state. Prompt recognition and treatment of PRES are vital to prevent long-term neurologic sequelae and death.

Original languageEnglish
Pages (from-to)358-367
Number of pages10
JournalHospital Medicine Clinics
Volume4
Issue number3
DOIs
StatePublished - Jul 1 2015

Keywords

  • Chemotherapy
  • Cyclosporine
  • Eclampsia
  • Hypertensive encephalopathy
  • Posterior reversible encephalopathy syndrome (PRES)
  • Preeclampsia
  • Reversible posterior leukoencephalopathy syndrome (RPLE)
  • Transplant

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