Positron Emission Tomography (PET) for Molecular Plant Imaging

Sergey Komarov, Yuan Chuan Tai

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

3 Scopus citations

Abstract

Positron emission tomography (PET) is an imaging technology that measures 3D spatial distribution and kinetics of radio-tagged biomolecules in a living subject quantitatively and nondestructively. Commonly used positron-emitting radionuclides include11C,13N, and15O, which are essential elements for plant growth. Combining radiotracer techniques with PET, this in vivo molecular imaging capability offers plant biologists a powerful tool for molecular phenotyping research. While PET is widely used clinically for cancer diagnosis and pre-clinically for drug development, it is an unfamiliar imaging tool for plant biologists. This chapter introduces the basic principles of PET, factors that affect the quantitative accuracy of PET when imaging plants, and techniques for administering radiotracers to plants for a variety of molecular plant imaging applications.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages97-118
Number of pages22
DOIs
StatePublished - 2022

Publication series

NameMethods in Molecular Biology
Volume2539
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • Molecular imaging
  • PET
  • Plant phenotyping
  • Positron emission tomography

Fingerprint

Dive into the research topics of 'Positron Emission Tomography (PET) for Molecular Plant Imaging'. Together they form a unique fingerprint.

Cite this