TY - JOUR
T1 - Positron emission tomography in the newborn
T2 - Effect of seizure on regional cerebral blood flow in an asphyxiated infant
AU - Perlman, Jeffrey M.
AU - Herscovitch, Peter
AU - Kreusser, Katherine L.
AU - Raichle, Marcus E.
AU - Volpe, Joseph J.
PY - 1985/2
Y1 - 1985/2
N2 - Regional cerebral blood flow (CBF) was measured by positron emission tomography (PET) with 150-labeled water in an asphyxi ated infant during a seizure. After intrauterine asphyxia, the infant had a syndrome characteristic of hypoxic-ischemic encephalopathy. During a PET scan on the second postnatal day, the infant had a focal seizure with deviation of eyes to the right and clonic jerking of the right arm. Regional blood flow was highest, about 80 ml/100 g/min, in the left temporal-parietalfrontal region of the left hemisphere, the site of origin of the seizure; blood flow in the same region on the other side was about 57 ml/100 g/min. These observations extend to the newborn previous demonstrations in older patients of a focal increase of CBF at the cerebral site of origin of a focal seizure.
AB - Regional cerebral blood flow (CBF) was measured by positron emission tomography (PET) with 150-labeled water in an asphyxi ated infant during a seizure. After intrauterine asphyxia, the infant had a syndrome characteristic of hypoxic-ischemic encephalopathy. During a PET scan on the second postnatal day, the infant had a focal seizure with deviation of eyes to the right and clonic jerking of the right arm. Regional blood flow was highest, about 80 ml/100 g/min, in the left temporal-parietalfrontal region of the left hemisphere, the site of origin of the seizure; blood flow in the same region on the other side was about 57 ml/100 g/min. These observations extend to the newborn previous demonstrations in older patients of a focal increase of CBF at the cerebral site of origin of a focal seizure.
UR - https://www.scopus.com/pages/publications/0021929543
U2 - 10.1212/wnl.35.2.244
DO - 10.1212/wnl.35.2.244
M3 - Article
C2 - 3871513
AN - SCOPUS:0021929543
SN - 0028-3878
VL - 35
SP - 244
EP - 247
JO - Neurology
JF - Neurology
IS - 2
ER -