The regulators of complement activation (RCA) constitute a tightly linked gene family that controls the activity of the complement system. Genetic polymorphisms have been reported for all of RCA genes at the DNA, RNA and/or protein levels. In addition, multiple RNA and/or protein products have been observed for most of these genes. These polymorphisms and variants are instrumental in the study of the structure, evolution and function of the RCA family.

Original languageEnglish
Pages (from-to)302-314
Number of pages13
JournalComplement and Inflammation
Issue number4-6
StatePublished - Jan 1 1990


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