Polycystic ovary syndrome and maternal obesity affect oocyte size in in vitro fertilization/intracytoplasmic sperm injection cycles

Kerri L. Marquard, Sahar M. Stephens, Emily S. Jungheim, Valerie S. Ratts, Randall R. Odem, Susan Lanzendorf, Kelle H. Moley

Research output: Contribution to journalArticlepeer-review

93 Scopus citations

Abstract

To determine the impact of maternal metabolic state on oocyte development in women undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI), we retrospectively analyzed a cohort of women with PCOS undergoing IVF/ICSI from 2008-2009 in a university-based fertility center. We determined that women with PCOS and obesity have smaller oocytes than control subjects, and that when further subdivided by body mass index, both PCOS and obesity independently influence oocyte size.

Original languageEnglish
Pages (from-to)2146-2149.e1
JournalFertility and Sterility
Volume95
Issue number6
DOIs
StatePublished - May 2011

Keywords

  • IVF/ICSI
  • PCOS
  • Polycystic ovary syndrome
  • obesity
  • oocyte size

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