Pneumonia in the solid organ transplant patient

Murali M. Chakinala, Elbert P. Trulock

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations

Abstract

Pneumonia remains a significant issue for the SOT patient because of impairments to host defenses, particularly from chronic immunosuppression. Owing to routine postoperative antibiotic prophylaxis and improved intensive care, the incidence of lower respiratory tract infections has declined, but these infections are still associated with significant morbidity and mortality. An understanding of the time line for pathogens after transplantation is crucial to the management of the SOT patient, particularly during the first 6 months. Unlike the management of immunocompetent patients, identification of the offending pathogens is crucial and requires an aggressive and vigilant diagnostic approach, often relying on early bronchoscopy.

Original languageEnglish
Pages (from-to)113-121
Number of pages9
JournalClinics in Chest Medicine
Volume26
Issue number1
DOIs
StatePublished - Mar 2005

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