TY - JOUR
T1 - Pneumonia in the solid organ transplant patient
AU - Chakinala, Murali M.
AU - Trulock, Elbert P.
PY - 2005/3
Y1 - 2005/3
N2 - Pneumonia remains a significant issue for the SOT patient because of impairments to host defenses, particularly from chronic immunosuppression. Owing to routine postoperative antibiotic prophylaxis and improved intensive care, the incidence of lower respiratory tract infections has declined, but these infections are still associated with significant morbidity and mortality. An understanding of the time line for pathogens after transplantation is crucial to the management of the SOT patient, particularly during the first 6 months. Unlike the management of immunocompetent patients, identification of the offending pathogens is crucial and requires an aggressive and vigilant diagnostic approach, often relying on early bronchoscopy.
AB - Pneumonia remains a significant issue for the SOT patient because of impairments to host defenses, particularly from chronic immunosuppression. Owing to routine postoperative antibiotic prophylaxis and improved intensive care, the incidence of lower respiratory tract infections has declined, but these infections are still associated with significant morbidity and mortality. An understanding of the time line for pathogens after transplantation is crucial to the management of the SOT patient, particularly during the first 6 months. Unlike the management of immunocompetent patients, identification of the offending pathogens is crucial and requires an aggressive and vigilant diagnostic approach, often relying on early bronchoscopy.
UR - http://www.scopus.com/inward/record.url?scp=15744393705&partnerID=8YFLogxK
U2 - 10.1016/j.ccm.2004.10.010
DO - 10.1016/j.ccm.2004.10.010
M3 - Review article
C2 - 15802173
AN - SCOPUS:15744393705
SN - 0272-5231
VL - 26
SP - 113
EP - 121
JO - Clinics in Chest Medicine
JF - Clinics in Chest Medicine
IS - 1
ER -