Abstract

In December 2008, plerixafor (Mozobil; Genzyme), an antagonist of the CXCR4 chemokine receptor, was approved by the US FDA for use in combination with granulocyte colony-stimulating factor to mobilize haematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin's lymphoma and multiple myeloma.

Original languageEnglish
Pages (from-to)105-107
Number of pages3
JournalNature Reviews Drug Discovery
Volume8
Issue number2
DOIs
StatePublished - 2009

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