Platelet Interactions With the Vessel Wall and Prosthetic Grafts

Brian G. Rubin, Samuel A. Santoro, Gregorio A. Sicard

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Most physicians are aware of the important role that platelets play in thrombus formation. The mechanisms that regulate platelet function are now understood at the molecular level. The same biologic processes that control platelet participation in the hemostatic process also allow platelets to interact with the vessel wall. This review will describe the interaction of platelets with the vessel wall and prosthetic grafts and the physiologic basis and clinical contribution of platelet inhibition to long-term graft patency.

Original languageEnglish
Pages (from-to)200-207
Number of pages8
JournalAnnals of Vascular Surgery
Issue number2
StatePublished - Jan 1 1993


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