Plasmacytoid dendritic cells: One-trick ponies or workhorses of the immune system?

Boris Reizis, Marco Colonna, Giorgio Trinchieri, Franck Barrat, Michel Gilliet

Research output: Contribution to journalReview articlepeer-review

87 Scopus citations

Abstract

Plasmacytoid dendritic cells (pDCs) were first described as interferon-producing cells and, for many years, their overlapping characteristics with both lymphocytes and classical dendritic cells (cDCs) created confusion over their exact ontogeny. In this Viewpoint article, Nature Reviews Immunology asks five leaders in the field to discuss their thoughts on the development and functions of pDCs do these cells serve mainly as a major source of type I interferons or do they also make other important contributions to immune responses?.

Original languageEnglish
Pages (from-to)558-565
Number of pages8
JournalNature Reviews Immunology
Volume11
Issue number8
DOIs
StatePublished - Aug 2011

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