Piezoelectric-transducer-based miniature catheter for ultrahigh-speed endoscopic optical coherence tomography

Tsung Han Tsai; Benjamin Potsaid; Martin F. Kraus; Chao Zhou; Yuankai K. Tao; Joachim Hornegger; James G. Fujimoto

doi:10.1364/BOE.2.002438

Piezoelectric-transducer-based miniature catheter for ultrahigh-speed endoscopic optical coherence tomography

Tsung Han Tsai, Benjamin Potsaid, Martin F. Kraus, Chao Zhou, Yuankai K. Tao, Joachim Hornegger, James G. Fujimoto

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

We developed a piezoelectric-transducer- (PZT) based miniature catheter with an outer diameter of 3.5 mm for ultrahigh-speed endoscopic optical coherence tomography (OCT). A miniaturized PZT bender actuates a fiber and the beam is scanned through a GRIN lens and micro-prism to provide high-speed, side-viewing capability. The probe optics can be pulled back over a long distance to acquire three-dimensional (3D) data sets covering a large area. Imaging is performed with 11 μm axial resolution in air (8 μm in tissue) and 20 μm transverse resolution, at 960 frames per second with a Fourier domain mode-locked laser operating at 480 kHz axial scan rate. Using a high-speed data acquisition system, endoscopic OCT imaging of the rabbit esophagus and colon in vivo and human colon specimens ex vivo is demonstrated.

Original language	English
Pages (from-to)	2438-2448
Number of pages	11
Journal	Biomedical Optics Express
Volume	2
Issue number	8
DOIs	https://doi.org/10.1364/BOE.2.002438
State	Published - Aug 1 2011

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abstract = "We developed a piezoelectric-transducer- (PZT) based miniature catheter with an outer diameter of 3.5 mm for ultrahigh-speed endoscopic optical coherence tomography (OCT). A miniaturized PZT bender actuates a fiber and the beam is scanned through a GRIN lens and micro-prism to provide high-speed, side-viewing capability. The probe optics can be pulled back over a long distance to acquire three-dimensional (3D) data sets covering a large area. Imaging is performed with 11 μm axial resolution in air (8 μm in tissue) and 20 μm transverse resolution, at 960 frames per second with a Fourier domain mode-locked laser operating at 480 kHz axial scan rate. Using a high-speed data acquisition system, endoscopic OCT imaging of the rabbit esophagus and colon in vivo and human colon specimens ex vivo is demonstrated.",

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AU - Tsai, Tsung Han

AU - Potsaid, Benjamin

AU - Kraus, Martin F.

AU - Zhou, Chao

AU - Tao, Yuankai K.

AU - Hornegger, Joachim

AU - Fujimoto, James G.

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AB - We developed a piezoelectric-transducer- (PZT) based miniature catheter with an outer diameter of 3.5 mm for ultrahigh-speed endoscopic optical coherence tomography (OCT). A miniaturized PZT bender actuates a fiber and the beam is scanned through a GRIN lens and micro-prism to provide high-speed, side-viewing capability. The probe optics can be pulled back over a long distance to acquire three-dimensional (3D) data sets covering a large area. Imaging is performed with 11 μm axial resolution in air (8 μm in tissue) and 20 μm transverse resolution, at 960 frames per second with a Fourier domain mode-locked laser operating at 480 kHz axial scan rate. Using a high-speed data acquisition system, endoscopic OCT imaging of the rabbit esophagus and colon in vivo and human colon specimens ex vivo is demonstrated.

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Piezoelectric-transducer-based miniature catheter for ultrahigh-speed endoscopic optical coherence tomography

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