Phototransduction: Phototransduction in cones

V. J. Kefalov

doi:10.1016/B978-0-12-374203-2.00189-5

Phototransduction: Phototransduction in cones

V. J. Kefalov

Department of Ophthalmology and Visual Sciences

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

6 Scopus citations

Abstract

Cones use a phototransduction cascade similar to the one found in rods to convert light into an electric signal. Yet, cones have unique physiological properties, which make them better suited than rods for function under daylight conditions. Cones are significantly less sensitive than rods and their photoresponses are several times faster than those of rods. In addition, cones recover their sensitivity significantly faster following exposure to bright light and are able to adapt to an enormous range of background lights. These important functional differences between rods and cones are achieved by fine modulation of the reactions in their respective phototransduction cascades.

Original language	English
Title of host publication	Encyclopedia of the Eye, Four-Volume Set
Publisher	Elsevier
Pages	389-396
Number of pages	8
ISBN (Electronic)	9780123742032
ISBN (Print)	9780123741981
DOIs	https://doi.org/10.1016/B978-0-12-374203-2.00189-5
State	Published - Jan 1 2010

Keywords

Arrestin
Chromophore
Dark adaptation
G-protein receptor kinase (GRK)
Guanylyl cyclase (GC)
Guanylyl cyclase activating protein (GCAP)
Light adaptation
Opsin
Phosphodiesterase (PDE)
Phototransduction
Pigment regeneration
Recoverin
Transducin
Visual cycle
cGMP-gated channel

Access to Document

10.1016/B978-0-12-374203-2.00189-5

Cite this

@inbook{90ea26d975434b828d07c38a20cc4da7,

title = "Phototransduction: Phototransduction in cones",

abstract = "Cones use a phototransduction cascade similar to the one found in rods to convert light into an electric signal. Yet, cones have unique physiological properties, which make them better suited than rods for function under daylight conditions. Cones are significantly less sensitive than rods and their photoresponses are several times faster than those of rods. In addition, cones recover their sensitivity significantly faster following exposure to bright light and are able to adapt to an enormous range of background lights. These important functional differences between rods and cones are achieved by fine modulation of the reactions in their respective phototransduction cascades.",

keywords = "Arrestin, Chromophore, Dark adaptation, G-protein receptor kinase (GRK), Guanylyl cyclase (GC), Guanylyl cyclase activating protein (GCAP), Light adaptation, Opsin, Phosphodiesterase (PDE), Phototransduction, Pigment regeneration, Recoverin, Transducin, Visual cycle, cGMP-gated channel",

author = "Kefalov, {V. J.}",

year = "2010",

month = jan,

day = "1",

doi = "10.1016/B978-0-12-374203-2.00189-5",

language = "English",

isbn = "9780123741981",

pages = "389--396",

booktitle = "Encyclopedia of the Eye, Four-Volume Set",

publisher = "Elsevier",

}

TY - CHAP

T1 - Phototransduction

T2 - Phototransduction in cones

AU - Kefalov, V. J.

PY - 2010/1/1

Y1 - 2010/1/1

N2 - Cones use a phototransduction cascade similar to the one found in rods to convert light into an electric signal. Yet, cones have unique physiological properties, which make them better suited than rods for function under daylight conditions. Cones are significantly less sensitive than rods and their photoresponses are several times faster than those of rods. In addition, cones recover their sensitivity significantly faster following exposure to bright light and are able to adapt to an enormous range of background lights. These important functional differences between rods and cones are achieved by fine modulation of the reactions in their respective phototransduction cascades.

AB - Cones use a phototransduction cascade similar to the one found in rods to convert light into an electric signal. Yet, cones have unique physiological properties, which make them better suited than rods for function under daylight conditions. Cones are significantly less sensitive than rods and their photoresponses are several times faster than those of rods. In addition, cones recover their sensitivity significantly faster following exposure to bright light and are able to adapt to an enormous range of background lights. These important functional differences between rods and cones are achieved by fine modulation of the reactions in their respective phototransduction cascades.

KW - Arrestin

KW - Chromophore

KW - Dark adaptation

KW - G-protein receptor kinase (GRK)

KW - Guanylyl cyclase (GC)

KW - Guanylyl cyclase activating protein (GCAP)

KW - Light adaptation

KW - Opsin

KW - Phosphodiesterase (PDE)

KW - Phototransduction

KW - Pigment regeneration

KW - Recoverin

KW - Transducin

KW - Visual cycle

KW - cGMP-gated channel

UR - http://www.scopus.com/inward/record.url?scp=79551629880&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-374203-2.00189-5

DO - 10.1016/B978-0-12-374203-2.00189-5

M3 - Chapter

AN - SCOPUS:85079829754

SN - 9780123741981

SP - 389

EP - 396

BT - Encyclopedia of the Eye, Four-Volume Set

PB - Elsevier

ER -

Phototransduction: Phototransduction in cones

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this