@inproceedings{48d0b814ccdf4ac288ee220ef937943d,
title = "Photoacoustic characterization of human ovarian tissue",
abstract = "Ovarian cancer has a five-year survival rate of only 30\%, which represents the highest mortality of all gynecologic cancers. The reason for that is that the current imaging techniques are not capable of detecting ovarian cancer early. Therefore, new imaging techniques, like photoacoustic imaging, that can provide functional and molecular contrasts are needed for improving the specificity of ovarian cancer detection and characterization. Using a coregistered photoacoustic and ultrasound imaging system we have studied thirty-one human ovaries ex vivo, including normal and diseased. In order to compare the photoacoustic imaging results from all the ovaries, a new parameter using the RF data has been derived. The preliminary results show higher optical absorption for abnormal and malignant ovaries than for normal postmenopausal ones. To estimate the quantitative optical absorption properties of the ovaries, additional ultrasound-guided diffuse optical tomography images have been acquired. Good agreement between the two techniques has been observed. These results demonstrate the potential of a co-registered photoacoustic and ultrasound imaging system for the diagnosis of ovarian cancer.",
keywords = "Cancer, Diffuse optical tomography, Imaging, Ovary, Photoacoustic, Ultrasound",
author = "Andres Aguirre and Yasaman Ardeshirpour and Sanders, \{Mary M.\} and Molly Brewer and Quing Zhu",
year = "2010",
doi = "10.1117/12.845828",
language = "English",
isbn = "9780819479600",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Photons Plus Ultrasound",
note = "Photons Plus Ultrasound: Imaging and Sensing 2010 ; Conference date: 24-01-2010 Through 26-01-2010",
}