Phosphorous-containing polymers for regenerative medicine

Brendan M. Watson, F. Kurtis Kasper, Antonios G. Mikos

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Disease and injury have resulted in a large, unmet need for functional tissue replacements. Polymeric scaffolds can be used to deliver cells and bioactive signals to address this need for regenerating damaged tissue. Phosphorous-containing polymers have been implemented to improve and accelerate the formation of native tissue both by mimicking the native role of phosphorous groups in the body and by attachment of other bioactive molecules. This manuscript reviews the synthesis, properties, and performance of phosphorous-containing polymers that can be useful in regenerative medicine applications.

Original languageEnglish
Article number025014
JournalBiomedical Materials (Bristol)
Volume9
Issue number2
DOIs
StatePublished - Apr 2014

Keywords

  • phosphorylcholine
  • polyphosphazene
  • polyphosphoester
  • regenerative medicine
  • tissue engineering

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