Phosphoinositide turnover provides a link in stimulus-response coupling

Philip W. Majerus; David B. Wilson; Thomas M. Connolly; Teresa E. Bross; Ellis J. Neufeld

doi:10.1016/0968-0004(85)90160-4

Phosphoinositide turnover provides a link in stimulus-response coupling

Philip W. Majerus, David B. Wilson, Thomas M. Connolly, Teresa E. Bross, Ellis J. Neufeld

Research output: Contribution to journal › Review article › peer-review

131 Scopus citations

Abstract

Much excitement has resulted from the discovery that phosphatidylinositol and its phosphorylated derivatives are storage forms of messenger molecules that can be released in response to specific extracellular signals. Signal molecules bind to cell surface receptors and the messenger molecules derived from the phosphoinositides couple the signal to a variety of responses within and between cells.

Original language	English
Pages (from-to)	168-171
Number of pages	4
Journal	Trends in biochemical sciences
Volume	10
Issue number	4
DOIs	https://doi.org/10.1016/0968-0004(85)90160-4
State	Published - Apr 1985

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title = "Phosphoinositide turnover provides a link in stimulus-response coupling",

abstract = "Much excitement has resulted from the discovery that phosphatidylinositol and its phosphorylated derivatives are storage forms of messenger molecules that can be released in response to specific extracellular signals. Signal molecules bind to cell surface receptors and the messenger molecules derived from the phosphoinositides couple the signal to a variety of responses within and between cells.",

author = "Majerus, {Philip W.} and Wilson, {David B.} and Connolly, {Thomas M.} and Bross, {Teresa E.} and Neufeld, {Ellis J.}",

year = "1985",

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T1 - Phosphoinositide turnover provides a link in stimulus-response coupling

AU - Majerus, Philip W.

AU - Wilson, David B.

AU - Connolly, Thomas M.

AU - Bross, Teresa E.

AU - Neufeld, Ellis J.

PY - 1985/4

Y1 - 1985/4

N2 - Much excitement has resulted from the discovery that phosphatidylinositol and its phosphorylated derivatives are storage forms of messenger molecules that can be released in response to specific extracellular signals. Signal molecules bind to cell surface receptors and the messenger molecules derived from the phosphoinositides couple the signal to a variety of responses within and between cells.

AB - Much excitement has resulted from the discovery that phosphatidylinositol and its phosphorylated derivatives are storage forms of messenger molecules that can be released in response to specific extracellular signals. Signal molecules bind to cell surface receptors and the messenger molecules derived from the phosphoinositides couple the signal to a variety of responses within and between cells.

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U2 - 10.1016/0968-0004(85)90160-4

DO - 10.1016/0968-0004(85)90160-4

M3 - Review article

AN - SCOPUS:0021837702

SN - 0968-0004

VL - 10

SP - 168

EP - 171

JO - Trends in biochemical sciences

JF - Trends in biochemical sciences

IS - 4

ER -

Phosphoinositide turnover provides a link in stimulus-response coupling

Abstract

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