Phosphoinositide turnover provides a link in stimulus-response coupling

Philip W. Majerus, David B. Wilson, Thomas M. Connolly, Teresa E. Bross, Ellis J. Neufeld

Research output: Contribution to journalReview articlepeer-review

127 Scopus citations


Much excitement has resulted from the discovery that phosphatidylinositol and its phosphorylated derivatives are storage forms of messenger molecules that can be released in response to specific extracellular signals. Signal molecules bind to cell surface receptors and the messenger molecules derived from the phosphoinositides couple the signal to a variety of responses within and between cells.

Original languageEnglish
Pages (from-to)168-171
Number of pages4
JournalTrends in biochemical sciences
Issue number4
StatePublished - Apr 1985


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