Abstract
The association of phenytoin and liver toxicity is well documented. This article describes a patient who underwent a transsphenoidal resection of a pituitary tumor who developed phenytoin-induced hepatotoxicity that was masked by the simultaneous administration of corticosteroids for treatment of cerebral edema. In a patient receiving both medications, the systemic manifestations of the hypersensitivity to phenytoin may go unrecognized, leading to delayed identification of a potentially lethal complication of this commonly prescribed anticonvulsant.
Original language | English |
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Pages (from-to) | 1196-1197 |
Number of pages | 2 |
Journal | Archives of internal medicine |
Volume | 149 |
Issue number | 5 |
DOIs | |
State | Published - 1989 |