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Phenotypic screening for pharmaceuticals using tissue constructs
T. Wakatsuki
, J. A. Fee
,
E. L. Elson
Department of Biochemistry & Molecular Biophysics
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
Center of Regenerative Medicine
DBBS - Molecular Cell Biology
Research output
:
Contribution to journal
›
Review article
›
peer-review
12
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Scopus citations
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Keyphrases
Tissue Constructs
100%
Phenotypic Screening
100%
Cellular Structure
66%
Molecular Screening
66%
Cell Behavior
33%
Tissue Structure
33%
Connective Tissue
33%
Blood Pressure
33%
Skeletal muscle
33%
Physiological Function
33%
Tissue Function
33%
Extracellular Matrix Protein 1 (ECM1)
33%
Contractile Force
33%
Vascular Smooth muscle Cells
33%
Cellular Response
33%
Fluorescence Method
33%
Mechanical Response
33%
Smooth muscle
33%
Heart muscle
33%
Cellular Contractile Force
33%
Muscle Tissue
33%
Active Pharmaceutical Ingredients
33%
Matrix Stiffness
33%
Matrix Structure
33%
Structure-activity
33%
Structural Response
33%
Pharmaceutical Activity
33%
Mechanical Function
33%
Target Molecules
33%
Fluorescence Fluctuations
33%
Confocal Detection
33%
Immunology and Microbiology
Cell Function
100%
Extracellular Matrix
100%
Connective Tissue
100%
Blood Pressure
100%
Muscle Tissue
100%
Vascular Smooth Muscle Cell
100%
Rigidity
100%
Tissue Structure
100%
Cell Structure
100%
Engineering
Contractile Force
100%
Molecular Level
100%
Mechanical Response
50%
Cellular Response
50%
Test System
50%
Matrix Component
50%
Matrix Structure
50%
Matrix Stiffness
50%
Target Molecule
50%
Structural Response
50%
Active Compound
50%
Biochemistry, Genetics and Molecular Biology
Enzyme
100%
Cell Function
100%
Blood Pressure
100%
Tissue Structure
100%
Rigidity
100%
Medicine and Dentistry
Phenotypic Screening
100%
Receptor
33%
Extracellular Matrix
33%
Connective Tissue
33%
Blood Pressure
33%
Cell Function
33%
Vascular Smooth Muscle Cell
33%
Enzymes
33%
Tissue Structure
33%
Cell Structure
33%
Pharmacology, Toxicology and Pharmaceutical Science
Receptor
100%
Enzymes
100%