TY - JOUR
T1 - PhasiRNAs in Plants
T2 - Their Biogenesis, genic sources, and roles in stress responses, development, and reproduction
AU - Liu, Yuanlong
AU - Teng, Chong
AU - Xia, Rui
AU - Meyers, Blake C.
N1 - Publisher Copyright:
© 2020 American Society of Plant Biologists. All rights reserved.
PY - 2020/10
Y1 - 2020/10
N2 - Phased secondary small interfering RNAs (phasiRNAs) constitute a major category of small RNAs in plants, but most of their functions are still poorly defined. Some phasiRNAs, known as trans-acting siRNAs, are known to target complementary mRNAs for degradation and to function in development. However, the targets or biological roles of other phasiRNAs remain speculative. New insights into phasiRNA biogenesis, their conservation, and their variation across the flowering plants continue to emerge due to the increased availability of plant genomic sequences, deeper and more sophisticated sequencing approaches, and improvements in computational biology and biochemical/molecular/genetic analyses. In this review, we survey recent progress in phasiRNA biology, with a particular focus on two classes associated with male reproduction: 21- nucleotide (accumulate early in anther ontogeny) and 24-nucloetide (produced in somatic cells during meiosis) phasiRNAs. We describe phasiRNA biogenesis, function, and evolution and define the unanswered questions that represent topics for future research.
AB - Phased secondary small interfering RNAs (phasiRNAs) constitute a major category of small RNAs in plants, but most of their functions are still poorly defined. Some phasiRNAs, known as trans-acting siRNAs, are known to target complementary mRNAs for degradation and to function in development. However, the targets or biological roles of other phasiRNAs remain speculative. New insights into phasiRNA biogenesis, their conservation, and their variation across the flowering plants continue to emerge due to the increased availability of plant genomic sequences, deeper and more sophisticated sequencing approaches, and improvements in computational biology and biochemical/molecular/genetic analyses. In this review, we survey recent progress in phasiRNA biology, with a particular focus on two classes associated with male reproduction: 21- nucleotide (accumulate early in anther ontogeny) and 24-nucloetide (produced in somatic cells during meiosis) phasiRNAs. We describe phasiRNA biogenesis, function, and evolution and define the unanswered questions that represent topics for future research.
UR - http://www.scopus.com/inward/record.url?scp=85092607084&partnerID=8YFLogxK
U2 - 10.1105/tpc.20.00335
DO - 10.1105/tpc.20.00335
M3 - Review article
C2 - 32817252
AN - SCOPUS:85092607084
SN - 1040-4651
VL - 32
SP - 3059
EP - 3080
JO - Plant Cell
JF - Plant Cell
IS - 10
ER -