Keyphrases
Estrogen Receptor-positive Metastatic Breast Cancer
100%
Endocrine Resistance
100%
Fulvestrant
100%
Phase I Trial
100%
Alisertib
100%
Dose Level
28%
Recommended Phase 2 Dose
28%
Aurora Kinase A (AURKA)
28%
Disease Progression
14%
Antitumor Activity
14%
Progression-free Survival
14%
Twice Daily
14%
Phase I Study
14%
Two-dose
14%
Median Progression-free Survival
14%
Dose Escalation
14%
Safety Profile
14%
Previously Treated
14%
Selective Inhibitor
14%
Endocrine Therapy
14%
Estrogen Receptor-positive Breast Cancer
14%
Breast Cancer Model
14%
Clinical Activity
14%
Resistance to Endocrine Therapy
14%
Fixed-dose Combination
14%
Aromatase Inhibitors
14%
Postmenopausal Patients
14%
Clinical Benefit Rate
14%
ER Expression
14%
Toxicity Activity
14%
Pharmacology, Toxicology and Pharmaceutical Science
Estrogen Receptor
100%
Metastatic Breast Cancer
100%
Fulvestrant
100%
Alisertib
100%
Endocrine Therapy
28%
Aurora A Kinase
28%
Progression Free Survival
14%
Cancer Model
14%
Disease Exacerbation
14%
Antitumor Activity
14%
Estrogen Receptor Positive Breast Cancer
14%
Survival Time
14%
Aromatase Inhibitor
14%
Phase I Trials
14%