Pharmacologic treatment of infants with neonatal abstinence syndrome in community hospitals compared to academic medical centers

Hayley Friedman; Gregory Parkinson; Hocine Tighiouart; Catherine Parkinson; David Tybor; Norma Terrin; Barry Lester; Karen Harvey-Wilkes; Jonathan M. Davis

doi:10.1038/s41372-018-0230-8

Pharmacologic treatment of infants with neonatal abstinence syndrome in community hospitals compared to academic medical centers

Hayley Friedman
, Gregory Parkinson
, Hocine Tighiouart
, Catherine Parkinson
, David Tybor
, Norma Terrin
, Barry Lester
, Karen Harvey-Wilkes
, Jonathan M. Davis

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Objective: To compare length of hospital stay (LOS), LOS due to neonatal abstinence syndrome (NAS), and duration of pharmacologic treatment in community or academic settings. Study design: One hundred-two infants exposed to opioids in utero at two community hospitals were compared to 256 from eight academic centers. All infants were managed with non-pharmacologic care followed by similar pharmacologic treatment options. Results: Two hundred-twelve infants received pharmacologic treatment for NAS. Mean LOS (24.7 ± 8.5 vs. 24.5 ± 11.3 days), LOS due to NAS (24.0 ± 8.2 vs. 23.3 ± 9.2 days), and duration of NAS treatment (19.3 ± 8.0 vs. 18.9 ± 9.2 days) were similar in community compared to academic medical centers. Conclusions: No significant differences were found in infants managed in the community compared to academic care settings. These findings support caring for opioid-exposed infants in both community and academic settings with the use of standardized care protocols.

Original language	English
Pages (from-to)	1651-1656
Number of pages	6
Journal	Journal of Perinatology
Volume	38
Issue number	12
DOIs	https://doi.org/10.1038/s41372-018-0230-8
State	Published - Dec 1 2018

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title = "Pharmacologic treatment of infants with neonatal abstinence syndrome in community hospitals compared to academic medical centers",

abstract = "Objective: To compare length of hospital stay (LOS), LOS due to neonatal abstinence syndrome (NAS), and duration of pharmacologic treatment in community or academic settings. Study design: One hundred-two infants exposed to opioids in utero at two community hospitals were compared to 256 from eight academic centers. All infants were managed with non-pharmacologic care followed by similar pharmacologic treatment options. Results: Two hundred-twelve infants received pharmacologic treatment for NAS. Mean LOS (24.7 ± 8.5 vs. 24.5 ± 11.3 days), LOS due to NAS (24.0 ± 8.2 vs. 23.3 ± 9.2 days), and duration of NAS treatment (19.3 ± 8.0 vs. 18.9 ± 9.2 days) were similar in community compared to academic medical centers. Conclusions: No significant differences were found in infants managed in the community compared to academic care settings. These findings support caring for opioid-exposed infants in both community and academic settings with the use of standardized care protocols.",

author = "Hayley Friedman and Gregory Parkinson and Hocine Tighiouart and Catherine Parkinson and David Tybor and Norma Terrin and Barry Lester and Karen Harvey-Wilkes and Davis, \{Jonathan M.\}",

note = "Funding Information: Funding This study was funded by NIDA grants R01DA032889-04 and 1R21DA041706-01 and a grant from the Charles H. Hood Foundation. Publisher Copyright: {\textcopyright} 2018, Springer Nature America, Inc.",

year = "2018",

month = dec,

day = "1",

doi = "10.1038/s41372-018-0230-8",

language = "English",

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T1 - Pharmacologic treatment of infants with neonatal abstinence syndrome in community hospitals compared to academic medical centers

AU - Friedman, Hayley

AU - Parkinson, Gregory

AU - Tighiouart, Hocine

AU - Parkinson, Catherine

AU - Tybor, David

AU - Terrin, Norma

AU - Lester, Barry

AU - Harvey-Wilkes, Karen

AU - Davis, Jonathan M.

N1 - Funding Information: Funding This study was funded by NIDA grants R01DA032889-04 and 1R21DA041706-01 and a grant from the Charles H. Hood Foundation. Publisher Copyright: © 2018, Springer Nature America, Inc.

PY - 2018/12/1

Y1 - 2018/12/1

N2 - Objective: To compare length of hospital stay (LOS), LOS due to neonatal abstinence syndrome (NAS), and duration of pharmacologic treatment in community or academic settings. Study design: One hundred-two infants exposed to opioids in utero at two community hospitals were compared to 256 from eight academic centers. All infants were managed with non-pharmacologic care followed by similar pharmacologic treatment options. Results: Two hundred-twelve infants received pharmacologic treatment for NAS. Mean LOS (24.7 ± 8.5 vs. 24.5 ± 11.3 days), LOS due to NAS (24.0 ± 8.2 vs. 23.3 ± 9.2 days), and duration of NAS treatment (19.3 ± 8.0 vs. 18.9 ± 9.2 days) were similar in community compared to academic medical centers. Conclusions: No significant differences were found in infants managed in the community compared to academic care settings. These findings support caring for opioid-exposed infants in both community and academic settings with the use of standardized care protocols.

AB - Objective: To compare length of hospital stay (LOS), LOS due to neonatal abstinence syndrome (NAS), and duration of pharmacologic treatment in community or academic settings. Study design: One hundred-two infants exposed to opioids in utero at two community hospitals were compared to 256 from eight academic centers. All infants were managed with non-pharmacologic care followed by similar pharmacologic treatment options. Results: Two hundred-twelve infants received pharmacologic treatment for NAS. Mean LOS (24.7 ± 8.5 vs. 24.5 ± 11.3 days), LOS due to NAS (24.0 ± 8.2 vs. 23.3 ± 9.2 days), and duration of NAS treatment (19.3 ± 8.0 vs. 18.9 ± 9.2 days) were similar in community compared to academic medical centers. Conclusions: No significant differences were found in infants managed in the community compared to academic care settings. These findings support caring for opioid-exposed infants in both community and academic settings with the use of standardized care protocols.

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SN - 0743-8346

VL - 38

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EP - 1656

JO - Journal of Perinatology

JF - Journal of Perinatology

IS - 12

ER -

Pharmacologic treatment of infants with neonatal abstinence syndrome in community hospitals compared to academic medical centers

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