Phagocytosis: Sweet Repulsions via the Glycocalyx

Sophia Maschalidi; Kodi S. Ravichandran

doi:10.1016/j.cub.2020.10.066

Phagocytosis: Sweet Repulsions via the Glycocalyx

Sophia Maschalidi
, Kodi S. Ravichandran

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

New work shows that the glycocalyx meshwork on the surface of macrophages prevents phagocytic receptors from binding their ligands by two means — electrostatic charge and steric hindrance. Components of this barrier are present on pathogenic and malignant targets that elude phagocytosis.

Original language	English
Pages (from-to)	R20-R22
Journal	Current Biology
Volume	31
Issue number	1
DOIs	https://doi.org/10.1016/j.cub.2020.10.066
State	Published - Jan 11 2021

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title = "Phagocytosis: Sweet Repulsions via the Glycocalyx",

abstract = "New work shows that the glycocalyx meshwork on the surface of macrophages prevents phagocytic receptors from binding their ligands by two means — electrostatic charge and steric hindrance. Components of this barrier are present on pathogenic and malignant targets that elude phagocytosis.",

author = "Sophia Maschalidi and Ravichandran, \{Kodi S.\}",

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AU - Ravichandran, Kodi S.

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N2 - New work shows that the glycocalyx meshwork on the surface of macrophages prevents phagocytic receptors from binding their ligands by two means — electrostatic charge and steric hindrance. Components of this barrier are present on pathogenic and malignant targets that elude phagocytosis.

AB - New work shows that the glycocalyx meshwork on the surface of macrophages prevents phagocytic receptors from binding their ligands by two means — electrostatic charge and steric hindrance. Components of this barrier are present on pathogenic and malignant targets that elude phagocytosis.

UR - https://www.scopus.com/pages/publications/85098797321

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DO - 10.1016/j.cub.2020.10.066

M3 - Article

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SN - 0960-9822

VL - 31

SP - R20-R22

JO - Current Biology

JF - Current Biology

IS - 1

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Phagocytosis: Sweet Repulsions via the Glycocalyx

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