Phagocytosis: Sweet Repulsions via the Glycocalyx

Sophia Maschalidi; Kodi S. Ravichandran

doi:10.1016/j.cub.2020.10.066

Phagocytosis: Sweet Repulsions via the Glycocalyx

Sophia Maschalidi, Kodi S. Ravichandran

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

New work shows that the glycocalyx meshwork on the surface of macrophages prevents phagocytic receptors from binding their ligands by two means — electrostatic charge and steric hindrance. Components of this barrier are present on pathogenic and malignant targets that elude phagocytosis.

Original language	English
Pages (from-to)	R20-R22
Journal	Current Biology
Volume	31
Issue number	1
DOIs	https://doi.org/10.1016/j.cub.2020.10.066
State	Published - Jan 11 2021

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title = "Phagocytosis: Sweet Repulsions via the Glycocalyx",

abstract = "New work shows that the glycocalyx meshwork on the surface of macrophages prevents phagocytic receptors from binding their ligands by two means — electrostatic charge and steric hindrance. Components of this barrier are present on pathogenic and malignant targets that elude phagocytosis.",

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Phagocytosis: Sweet Repulsions via the Glycocalyx

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