TY - JOUR
T1 - Personalizing acute therapies for ischemic stroke
AU - Lee, Jin Moo
AU - Dziedzic, Tomasz
N1 - Funding Information:
T.D. serves on the editorial board of American Journal of Alzheimer’s Disease & Other Dementias. J.-M.L. receives research funding from NIH (R01NS084028, R01NS085419, R01NS09469, and R21AG05533301) and the Barnes-Jewish Hospital Foundation. Go to Neurology.org/N for full disclosures.
Publisher Copyright:
© 2018 American Academy of Neurology.
PY - 2018/3/20
Y1 - 2018/3/20
N2 - The last 2 years has seen unprecedented advances in acute stroke care. In 2015, multiple independent clinical trials demonstrated that endovascular thrombectomy early after acute ischemic stroke (AIS) onset is highly effective for reducing long-term disability. 1-5 More recently, the DAWN trial demonstrated the efficacy of thrombectomy in select patients up to 24 hours after stroke onset. 6 Critical to the success of these trials has been the use of rapid and robust neuroimaging methods that helped select appropriate patients based on clot location or core/penumbral signatures. Neuroimaging has become the precision medicine equivalent in AIS, personalizing care based on advanced imaging measures.
AB - The last 2 years has seen unprecedented advances in acute stroke care. In 2015, multiple independent clinical trials demonstrated that endovascular thrombectomy early after acute ischemic stroke (AIS) onset is highly effective for reducing long-term disability. 1-5 More recently, the DAWN trial demonstrated the efficacy of thrombectomy in select patients up to 24 hours after stroke onset. 6 Critical to the success of these trials has been the use of rapid and robust neuroimaging methods that helped select appropriate patients based on clot location or core/penumbral signatures. Neuroimaging has become the precision medicine equivalent in AIS, personalizing care based on advanced imaging measures.
UR - http://www.scopus.com/inward/record.url?scp=85053913568&partnerID=8YFLogxK
U2 - 10.1212/WNL.0000000000005169
DO - 10.1212/WNL.0000000000005169
M3 - Review article
C2 - 29444965
AN - SCOPUS:85053913568
VL - 90
SP - 535
EP - 536
JO - Neurology
JF - Neurology
SN - 0028-3878
IS - 12
ER -