Abstract
Introduction: We hypothesized that the probability of personality disorder ('PROB') predicted by the Temperament and Character Inventory ('TCI') would decline after successful pharmacotherapy of depression. Methods: We administered a computerized version of the TCI to 15 patients with DSM-III-R major depression, before and after treatment with serotonergic antidepressants. Results: PROB declined from 58.9% ± 18.0% to 42.4% ± 22.8% (P < 0.003), due to a significant increase in the Self-Directedness scale. This change in PROB correlated with improvement in self-rated severity of depression (P < 0.02). Conclusion: TCI prediction of personality disorder is susceptible to state effects of depression.
Original language | English |
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Pages (from-to) | 11-18 |
Number of pages | 8 |
Journal | Journal of affective disorders |
Volume | 43 |
Issue number | 1 |
DOIs | |
State | Published - Mar 1 1997 |
Keywords
- Character
- Depressive disorder
- Personality disorders
- Personality inventory
- Psychometrics
- Reproducibility of results