TY - JOUR
T1 - Persistent edematous-plaque photosensitivity observed with sitagliptin phosphate (Januvia®)
AU - Stricklin, Sherea M.
AU - Stoecker, William V.
AU - Rader, Ryan K.
AU - Hood, Antoinette F.
AU - Litt, Jerome Z.
AU - Schuman, Thomas P.
PY - 2012/2
Y1 - 2012/2
N2 - Photosensitivity to sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, is reported. No previous reports of photosensitivity to any DPP-4 inhibitors are known. Physical examination of the patient revealed edematous plaques confined to sun-exposed areas of the skin. An unusual finding in this case was the spongy sensation upon palpation of the plaques. Histopathology revealed parakeratosis and abundant eosinophils, supporting the clinical impression of cutaneous drug sensitivity. The eruption finally cleared, approximately two years after onset.
AB - Photosensitivity to sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, is reported. No previous reports of photosensitivity to any DPP-4 inhibitors are known. Physical examination of the patient revealed edematous plaques confined to sun-exposed areas of the skin. An unusual finding in this case was the spongy sensation upon palpation of the plaques. Histopathology revealed parakeratosis and abundant eosinophils, supporting the clinical impression of cutaneous drug sensitivity. The eruption finally cleared, approximately two years after onset.
UR - http://www.scopus.com/inward/record.url?scp=84857808958&partnerID=8YFLogxK
M3 - Article
C2 - 22398230
AN - SCOPUS:84857808958
SN - 1087-2108
VL - 18
JO - Dermatology Online Journal
JF - Dermatology Online Journal
IS - 2
ER -