Persistent edematous-plaque photosensitivity observed with sitagliptin phosphate (Januvia®)

Sherea M. Stricklin, William V. Stoecker, Ryan K. Rader, Antoinette F. Hood, Jerome Z. Litt, Thomas P. Schuman

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Photosensitivity to sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, is reported. No previous reports of photosensitivity to any DPP-4 inhibitors are known. Physical examination of the patient revealed edematous plaques confined to sun-exposed areas of the skin. An unusual finding in this case was the spongy sensation upon palpation of the plaques. Histopathology revealed parakeratosis and abundant eosinophils, supporting the clinical impression of cutaneous drug sensitivity. The eruption finally cleared, approximately two years after onset.

Original languageEnglish
JournalDermatology Online Journal
Volume18
Issue number2
StatePublished - Feb 2012

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